Periodontitis and Accelerated Biological Aging: A Geroscience Approach

• Published in: Journal of dental research Vol. 101; no. 2; pp. 125 - 132
• Main Authors: Baima, G., Romandini, M., Citterio, F., Romano, F., Aimetti, M.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.02.2022; SAGE PUBLICATIONS, INC
• Subjects: Age; Aging; Alveolar bone; Alveolar Bone Loss; Biomarkers; Bone resorption; Cell therapy; Chronic infection; Epidemiology; Geroscience; Gum disease; Homeostasis; Humans; Hyperglycemia; Lipopolysaccharides; Morbidity; Mortality; Oral cavity; Osteocytes; Periodontitis; Risk factors; Senescence; Stem cells; Systemic diseases; Telomeres; oral-systemic diseases; immunity; periodontal diseases; inflammation; biomarkers; periodontal medicine

As the whole world is epidemically aging, the burden of periodontitis and tooth loss is becoming a major health concern. Growing meta-epidemiological data implicate chronic systemic inflammation/infection due to periodontitis as an independent risk factor for aging-related diseases and mortality. Ho...