Nonclinical phenotypic and genotypic analyses of a Phase 1 pediatric respiratory syncytial virus vaccine candidate MEDI-559 (rA2cp248/404/1030ΔSH) at permissive and non-permissive temperatures - Schickli, Jeanne H.; Kaur, Jasmine; Tang, Roderick S. (Virus research, 2012)
Keywords: Animals; genes; genetic background; Humans; immune response; infants; leucine; Live attenuated virus; lungs; Mutation; phenotype; Rats; Respiratory syncytial virus; Respiratory Syncytial Virus Vaccines - genetics; Respiratory Syncytial Viruses - genetics; Respiratory Syncytial Viruses - physiology; Respiratory Syncytial Viruses - radiation effects; RNA, Viral - genetics; RSV vaccine; serine; Sigmodon; Temperature; Temperature sensitive virus; tyrosine; vaccines; Vaccines, Attenuated - genetics; Viral Plaque Assay; Viral Proteins; Virus Replication - radiation effects; viruses; RSV vaccine; Temperature sensitive virus; Live attenuated virus