Single- and Multiple-Dose Pharmacokinetics of Long-acting Injectable Naltrexone - Dunbar, Joi L.; Turncliff, Ryan Z.; Dong, Qunming; Silverman, Bernard L.; Ehrich, Elliot W.; Lasseter, Kenneth C. (Alcoholism, clinical and experimental research, 2006)
Keywords: Administration, Oral; Adolescent; Adult; Alcohol Deterrents; Alcoholism and acute alcohol poisoning; Area Under Curve; Biological and medical sciences; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Extended-Release Preparation; Female; Half-Life; Humans; Injections; Lactic Acid; Long-acting Injectable; Male; Medical sciences; Microspheres; Middle Aged; Naltrexone; Naltrexone - administration & dosage; Naltrexone - adverse effects; Naltrexone - analogs & derivatives; Naltrexone - blood; Naltrexone - pharmacokinetics; Narcotic Antagonists - administration & dosage; Narcotic Antagonists - adverse effects; Narcotic Antagonists - pharmacokinetics; Pharmacokinetics; Polyglycolic Acid; Polymers; Sex Characteristics; Toxicology; Morphinan derivatives; Multiple dose; Narcotic antagonist; Preparation; Extended-Release Preparation; Long-acting Injectable; Naltrexone; Pharmacokinetics; Release