Utility of red blood cell acetylcholinesterase measurement in mechanically ventilated subjects after organophosphate poisoning

• Published in: Respiratory care Vol. 59; no. 9; p. 1360
• Main Authors: Moon, Jeongmi, Chun, Byeongjo
• Format: Journal Article
• Language: English
• Published: United States 01.09.2014
• Subjects: Acetylcholinesterase - blood; Erythrocytes - enzymology; Female; Humans; Male; Middle Aged; Organophosphate Poisoning - enzymology; Organophosphate Poisoning - therapy; Organophosphates - chemistry; Organophosphates - toxicity; Predictive Value of Tests; Respiration, Artificial; Retrospective Studies; Time Factors; Ventilator Weaning; acetylcholinesterase; organophosphates; pesticide; ventilator weaning

Many patients with organophosphate poisoning require mechanical ventilation. Muscle acetylcholinesterase (AChE) activity determines the impairment of muscle force generation, and red blood cell (RBC) AChE has been regarded as a surrogate for muscle AChE in organophosphate poisoning. Therefore, this...