Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions - Kaffe, Eleanna; Roulis, Manolis; Zhao, Jun; Qu, Rihao; Sefik, Esen; Mirza, Haris; Zhou, Jing; Zheng, Yunjiang; Charkoftaki, Georgia; Vasiliou, Vasilis; Vatner, Daniel F.; Mehal, Wajahat Z.; et al. (Cell, 2023)
Keywords: Animals; bile acid conjugation; bile acids; cholesterol; Endothelial Cells - metabolism; fatty liver; fibrosis; Fibrosis - metabolism; FZD5; hepatocytes; Hepatocytes - metabolism; human diseases; humanized liver; Humans; Kupffer Cells - metabolism; lipidomics; liver; Liver - cytology; Liver - metabolism; liver sinusoidal endothelial cells; metabolism; Mice; non-alcoholic fatty liver disease; Non-alcoholic Fatty Liver Disease - metabolism; species; stellate cells; wnt proteins; WNT2; bile acid conjugation; non-alcoholic fatty liver disease; FZD5; stellate cells; cholesterol; liver sinusoidal endothelial cells; fibrosis; humanized liver; WNT2; lipidomics