A reciprocal relationship between markers of genomic DNA damage and alpha-synuclein pathology in dementia with Lewy bodies - Koss, David J.; Todd, Olivia; Menon, Hariharan; Anderson, Zoe; Yang, Tamsin; Findlay, Lucas; Graham, Ben; Palmowski, Pawel; Porter, Andrew; Morrice, Nicola; Walker, Lauren; Attems, Johannes; et al. (Molecular neurodegeneration, 2025)
Keywords: Aged; Aged, 80 and over; alpha-Synuclein - genetics; alpha-Synuclein - metabolism; Alpha-synuclein; DNA damage; synucleinopathy; Parkinson’s disease; Animals; Biomarkers - metabolism; Brain; Dementia with Lewy bodies; DNA; DNA damage; DNA Damage - physiology; Ethylenediaminetetraacetic acid; Female; Humans; Lewy Bodies - metabolism; Lewy Bodies - pathology; Lewy Body Disease - genetics; Lewy Body Disease - metabolism; Lewy Body Disease - pathology; Male; Medical research; Medicine, Experimental; Mice; Mice, Transgenic; Nervous system diseases; Neurons; Neurophysiology; Physiological aspects; Proteins; United Kingdom; Alpha-synuclein; DNA damage; synucleinopathy; Parkinson’s disease; Dementia with Lewy bodies