Functional resilience of C57BL/6J mouse heart to dietary fat overload - Tadinada, Satya Murthy; Weatherford, Eric T.; Collins, Greg V.; Bhardwaj, Gourav; Cochran, Jesse; Kutschke, William; Zimmerman, Kathy; Bosko, Alyssa; O’Neill, Brian T.; Weiss, Robert M.; Abel, E. Dale (American journal of physiology. Heart and circulatory physiology, 2021)
Keywords: Abnormalities; Age Factors; Animals; b-Adrenergic-receptor kinase; Cardiac function; Cardiomyopathy; CD36 antigen; Coconut oil; Collagen; Congestive heart failure; Diabetes; Diabetes mellitus; Diabetic Cardiomyopathies - enzymology; Diabetic Cardiomyopathies - etiology; Diabetic Cardiomyopathies - pathology; Diabetic Cardiomyopathies - physiopathology; Diet; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Fatty acids; Female; Fibrosis; G protein-coupled receptor kinase; G protein-coupled receptor kinase 2; G-Protein-Coupled Receptor Kinase 2 - genetics; G-Protein-Coupled Receptor Kinase 2 - metabolism; Gene expression; Heart; Hemodynamics; High fat diet; Hypertrophy; Hypertrophy, Left Ventricular - enzymology; Hypertrophy, Left Ventricular - etiology; Hypertrophy, Left Ventricular - pathology; Hypertrophy, Left Ventricular - physiopathology; Isoforms; Kinases; Lipids; Male; Matrix metalloproteinase; Matrix metalloproteinases; Metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondria, Heart - enzymology; Mitochondria, Heart - pathology; Molecular modelling; Muscle contraction; Myocardium - enzymology; Myocardium - pathology; Obesity - complications; Stroke Volume; Ventricle; Ventricular Dysfunction, Left - enzymology; Ventricular Dysfunction, Left - etiology; Ventricular Dysfunction, Left - pathology; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left; Ventricular Remodeling; cardiac function; type 2 diabetes; diabetic cardiomyopathy; mitochondria; high-fat diet