Development and validation of retrospective spinal cord motion time-course estimates (RESPITE) for spin-echo spinal fMRI: Improved sensitivity and specificity by means of a motion-compensating general linear model analysis

• Published in: NeuroImage (Orlando, Fla.) Vol. 44; no. 2; pp. 421 - 427
• Main Authors: Figley, Chase R., Stroman, Patrick W.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.01.2009; Elsevier Limited
• Subjects: Algorithms; Analysis; Brain; Cervical Vertebrae; Computer Simulation; Echo-Planar Imaging - methods; Estimates; Evoked Potentials - physiology; fMRI; General linear model (GLM); Human; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Linear Models; Magnetic Resonance Imaging - methods; Methods; Models, Neurological; Motion; Noise; Physiological motion; Reproducibility of Results; Retrospective motion correction; Retrospective Studies; Sensitivity and Specificity; Spinal cord; Spinal Cord - physiology; Studies; Vertebrae; Human; fMRI; General linear model (GLM); Spinal cord; Analysis; Retrospective motion correction; Physiological motion

Cervical spinal cord displacements have recently been measured in relation to the cardiac cycle, substantiating that cord motion in this region reduces both the sensitivity and reproducibility of functional magnetic resonance imaging of the spinal cord (spinal fMRI). Given the ubiquitous and complex...