Scintigraphic assessment of radio-aerosol pulmonary deposition with the acapella positive expiratory pressure device and various nebulizer configurations

• Published in: Respiratory care Vol. 59; no. 3; pp. 328 - 333
• Main Authors: Mesquita, Fabrício O S, Galindo-Filho, Valdecir C, Neto, João Luis F, Galvão, André M, Brandão, Simone C S, Fink, James B, Dornelas-de-Andrade, Armèle
• Format: Journal Article
• Language: English
• Published: United States Daedalus Enterprises, Inc 01.03.2014
• Subjects: Adult; Aerosol therapy; Aerosols - administration & dosage; Cross-Over Studies; Equipment Design; Humans; Lung - diagnostic imaging; Male; Medical research; Medicine, Experimental; Nebulizers and Vaporizers; Patient outcomes; Positive-Pressure Respiration - instrumentation; Radionuclide Imaging; Young Adult; positive expiratory pressure; nebulizer; oscillatory PEP; aerosol deposition; aerosol; pulmonary scintigraphy

The Acapella device produces high-frequency oscillations and positive expiratory pressure to promote bronchial secretion clearance. Its performance during aerosol delivery has not been described. We evaluated the effect of nebulizer and Acapella configuration on pulmonary deposition of radio-tagged...