Performance Evaluation of the Preanalytic Module of the ACL TOP 750 Hemostasis Lab System

• Published in: Annals of laboratory medicine Vol. 38; no. 5; pp. 484 - 486
• Main Authors: Kwoun, Woo Jae, Ahn, Jeong Yeal, Park, Pil Whan, Seo, Yiel Hea, Kim, Kyung Hee, Seo, Ja Young, Jeong, Ji Hun, Lee, Hwan Tae
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society for Laboratory Medicine 01.09.2018; 대한진단검사의학회
• Subjects: Blood Coagulation Tests - instrumentation; Blood Coagulation Tests - methods; Blood Coagulation Tests - standards; Hemoglobins - analysis; Hemoglobins - standards; Hemolysis; Humans; Hyperlipidemias - blood; Hyperlipidemias - pathology; Jaundice - blood; Jaundice - pathology; Letter to the Editor; Linear Models; Reference Values; 병리학
• DOI: 10.3343/alm.2018.38.5.484
• ISSN: 2234-3806

Dear Editor, Hemolysis, icterus, and lipemia are important preanalytic sources of errors in coagulation testing of blood samples, besides sample-to-anticoagulant ratio, transport stability, and storage temperature. Lipemia (13%), hyperbilirubinemia (11%), and hemolysis (4%) in whole blood cause errors in coagulation testing [1, 2]. Hemoglobin, bilirubin, and triglyceride are major interfering substances that affect test results by spectral overlap [3, 4]. Hemolytic, icteric, and lipemic (HIL) sample check functions have been implemented in the preanalytic module of the ACL TOP family 50 series spectrophotometric hemostasis equipment (Instrumentation Laboratory Company, Bedford, MA, USA) to support preanalytic sample evaluation. We evaluated the performance of the ACL TOP 750 preanalytic module, using patient samples. KCI Citation Count: 0