Identification of California Condor Estrogen Receptors 1 and 2 and Their Activation by Endocrine Disrupting Chemicals

• Published in: Endocrinology (Philadelphia) Vol. 156; no. 12; pp. 4448 - 4457
• Main Authors: Felton, Rachel G, Steiner, Cynthia C, Durrant, Barbara S, Keisler, Duane H, Milnes, Matthew R, Tubbs, Christopher W
• Format: Journal Article
• Language: English
• Published: United States Endocrine Society 01.12.2015; Oxford University Press
• Subjects: Amino acids; Animals; Benzhydryl Compounds - pharmacology; Birds - genetics; Bisphenol A; California; Coastal ecology; Coastal zone; Data recovery; DDE; DDT; DDT - pharmacology; Dieldrin; Dieldrin - pharmacology; Disruption; Egg shells; Endocrine disruptors; Endocrine Disruptors - pharmacology; Environmental Pollutants - pharmacology; Estrogen Receptor alpha - drug effects; Estrogen Receptor alpha - genetics; Estrogen Receptor beta - drug effects; Estrogen Receptor beta - genetics; Estrogen receptors; Estrogens; Gymnogyps californianus; Hydrocarbons, Chlorinated - pharmacology; Insecticides; Marine chemistry; Marine mammals; Metabolites; Mutation; Nitrous oxide; PCB; Pesticides; Phenols - pharmacology; Phylogeny; Plasma levels; Polychlorinated biphenyls; Polychlorinated Biphenyls - pharmacology; Positive selection; Raptors - genetics; Receptor mechanisms; Receptors; Species; California; United States > US

Recently, California condors (Gymnogyps californianus) have been reintroduced to coastal regions of California where they feed on marine mammal carcasses. There is evidence that coastal-dwelling condors experience reproductive issues, such as eggshell thinning, likely resulting from exposure to endo...