Spindle epithelial tumor with thymus-like differentiation of the thyroid in a 70-year-old man

Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a very rare tumor of the thyroid gland mostly occurring in young patients. The imaging findings of SETTLE tumors are yet to be defined. However, they are usually described as well-defined heterogeneously enhanced masses on CT scan...

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Published inAnnals of surgical treatment and research Vol. 94; no. 6; pp. 337 - 341
Main Authors Lee, Sunhye, Kim, Yon Seon, Lee, Jeong Hyeon, Hwang, Sung Ho, Oh, Yu-Hwan, Ko, Byung Kyun, Ham, Soo-Youn
Format Journal Article
LanguageEnglish
Published Korea (South) 대한외과학회 01.06.2018
The Korean Surgical Society
Subjects
Case Report
일반외과학
Thyroid neoplasms
X-ray computed tomography
Surgery
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Abstract Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a very rare tumor of the thyroid gland mostly occurring in young patients. The imaging findings of SETTLE tumors are yet to be defined. However, they are usually described as well-defined heterogeneously enhanced masses on CT scan. The current case has the potential growth as compared with a 2009 chest radiography. We took into account the possibility of SETTLE in the case of a bulky mass in patients over 70 years old, particularly in the lower neck. Herein, we report a case of the oldest patient so far. The patient underwent a right lobectomy of the thyroid and mass excision. Follow-up CT scans after 6 months revealed no local recurrence. Surgery is the gold standard treatment for SETTLE. Chemotherapy and radiotherapy could be another possible option for patients with advanced stage SETTLE.
AbstractList Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a very rare tumor of the thyroid gland mostly occurring in young patients. The imaging findings of SETTLE tumors are yet to be defined. However, they are usually described as well-defined heterogeneously enhanced masses on CT scan. The current case has the potential growth as compared with a 2009 chest radiography. We took into account the possibility of SETTLE in the case of a bulky mass in patients over 70 years old, particularly in the lower neck. Herein, we report a case of the oldest patient so far. The patient underwent a right lobectomy of the thyroid and mass excision. Follow-up CT scans after 6 months revealed no local recurrence. Surgery is the gold standard treatment for SETTLE. Chemotherapy and radiotherapy could be another possible option for patients with advanced stage SETTLE. KCI Citation Count: 2
Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a very rare tumor of the thyroid gland mostly occurring in young patients. The imaging findings of SETTLE tumors are yet to be defined. However, they are usually described as well-defined heterogeneously enhanced masses on CT scan. The current case has the potential growth as compared with a 2009 chest radiography. We took into account the possibility of SETTLE in the case of a bulky mass in patients over 70 years old, particularly in the lower neck. Herein, we report a case of the oldest patient so far. The patient underwent a right lobectomy of the thyroid and mass excision. Follow-up CT scans after 6 months revealed no local recurrence. Surgery is the gold standard treatment for SETTLE. Chemotherapy and radiotherapy could be another possible option for patients with advanced stage SETTLE.
Author Jeong Hyeon Lee
Yu-Hwan Oh
Byung Kyun Ko
Sung Ho Hwang
Sunhye Lee
Yon Seon Kim
Soo-Youn Ham
AuthorAffiliation 4 Department of Radiology, Kangbuk Samsung Medical Center, Seoul, Korea
2 Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
1 Department of Radiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
3 Department of Pathology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
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Cites_doi 10.1007/s12020-015-0716-5
10.5858/2006-130-405-AETIAY
10.1016/0046-8177(91)90083-2
10.1002/lary.5540861212
10.1097/00000478-198507000-00007
10.1590/S0004-27302010000700011
10.1385/EP:16:2:139
10.1038/modpathol.3880212
10.3109/00313020903494037
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Keywords Thyroid neoplasms
X-ray computed tomography
Surgery
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References Murao (10.4174/astr.2018.94.6.337_ref6) 1979; 29
Harach (10.4174/astr.2018.94.6.337_ref2) 1985; 9
Ippolito (10.4174/astr.2018.94.6.337_ref7) 2016; 51
Magnata Filho (10.4174/astr.2018.94.6.337_ref8) 2010; 54
Trabelsi (10.4174/astr.2018.94.6.337_ref9) 2006; 130
Lee (10.4174/astr.2018.94.6.337_ref10) 2010; 42
Cheuk (10.4174/astr.2018.94.6.337_ref3) 2000; 13
Abrosimov (10.4174/astr.2018.94.6.337_ref4) 2005; 16
Chan (10.4174/astr.2018.94.6.337_ref1) 1991; 22
Levey (10.4174/astr.2018.94.6.337_ref5) 1976; 86
References_xml – volume: 51
  start-page: 402
  year: 2016
  ident: 10.4174/astr.2018.94.6.337_ref7
  publication-title: Endocrine
  doi: 10.1007/s12020-015-0716-5
  contributor:
    fullname: Ippolito
– volume: 130
  start-page: 405
  year: 2006
  ident: 10.4174/astr.2018.94.6.337_ref9
  publication-title: Arch Pathol Lab Med
  doi: 10.5858/2006-130-405-AETIAY
  contributor:
    fullname: Trabelsi
– volume: 22
  start-page: 349
  year: 1991
  ident: 10.4174/astr.2018.94.6.337_ref1
  publication-title: Hum Pathol
  doi: 10.1016/0046-8177(91)90083-2
  contributor:
    fullname: Chan
– volume: 86
  start-page: 1864
  year: 1976
  ident: 10.4174/astr.2018.94.6.337_ref5
  publication-title: Laryngoscope
  doi: 10.1002/lary.5540861212
  contributor:
    fullname: Levey
– volume: 9
  start-page: 525
  year: 1985
  ident: 10.4174/astr.2018.94.6.337_ref2
  publication-title: Am J Surg Pathol
  doi: 10.1097/00000478-198507000-00007
  contributor:
    fullname: Harach
– volume: 29
  start-page: 109
  year: 1979
  ident: 10.4174/astr.2018.94.6.337_ref6
  publication-title: Acta Pathol Jpn
  contributor:
    fullname: Murao
– volume: 54
  start-page: 657
  year: 2010
  ident: 10.4174/astr.2018.94.6.337_ref8
  publication-title: Arq Bras Endocrinol Metabol
  doi: 10.1590/S0004-27302010000700011
  contributor:
    fullname: Magnata Filho
– volume: 16
  start-page: 139
  year: 2005
  ident: 10.4174/astr.2018.94.6.337_ref4
  publication-title: Endocr Pathol
  doi: 10.1385/EP:16:2:139
  contributor:
    fullname: Abrosimov
– volume: 13
  start-page: 1150
  year: 2000
  ident: 10.4174/astr.2018.94.6.337_ref3
  publication-title: Mod Pathol
  doi: 10.1038/modpathol.3880212
  contributor:
    fullname: Cheuk
– volume: 42
  start-page: 188
  year: 2010
  ident: 10.4174/astr.2018.94.6.337_ref10
  publication-title: Pathology
  doi: 10.3109/00313020903494037
  contributor:
    fullname: Lee
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Title Spindle epithelial tumor with thymus-like differentiation of the thyroid in a 70-year-old man
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