Stem Cell Surgery and Growth Factors in Retinitis Pigmentosa Patients: Pilot Study after Literature Review

• Published in: Biomedicines Vol. 7; no. 4; p. 94
• Main Authors: Limoli, Paolo Giuseppe, Vingolo, Enzo Maria, Limoli, Celeste, Nebbioso, Marcella
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.11.2019; MDPI
• Subjects: Apoptosis; Autografts; Diabetic retinopathy; Disease; Growth factors; Informed consent; Literature reviews; Medical prognosis; Mesenchyme; Patients; Photoreceptors; Retina; Retinal degeneration; Retinitis; Retinitis pigmentosa; Stem cells; Surgery; Transplants & implants; Vitamin deficiency; Italy; autograft; hereditary retinal disease; mesenchymal stem cell (MSC); spectral domain-optical coherence tomography (SD-OCT); retinitis pigmentosa; induced pluripotent stem cells (iPSCs); embryonic stem cells (ESCs); growth factor (GF); limoli retinal restoration technique (LRRT)
• ISSN: 2227-9059; 2227-9059
• DOI: 10.3390/biomedicines7040094

To evaluate whether grafting of autologous mesenchymal cells, adipose-derived stem cells, and platelet-rich plasma into the supracoroideal space by surgical treatment with the Limoli retinal restoration technique (LRRT) can exert a beneficial effect in retinitis pigmentosa (RP) patients. Twenty-one...