Abnormal Sleep Delta Rhythm and Interregional Phase Synchrony in Patients with Restless Legs Syndrome and Their Reversal by Dopamine Agonist Treatment

The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of treatment with a dopamine agonist. Based on whole-brain electroencephalograms, we attempted to verify alterations in the functional network a...

Full description

Saved in:
Bibliographic Details
Published inJournal of clinical neurology (Seoul, Korea) Vol. 13; no. 4; pp. 340 - 350
Main Authors Choi, Jeong Woo, Jeong, Min Hee, Her, Seong Jin, Lee, Byeong Uk, Cha, Kwang Su, Jung, Ki Young, Kim, Kyung Hwan
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Neurological Association 01.10.2017
대한신경과학회
Subjects
Original
신경과학
dopamine agonist treatment
spectral power
polysomnography
functional network
restless legs syndrome
delta rhythm
Online AccessGet full text

Cover

Abstract The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of treatment with a dopamine agonist. Based on whole-brain electroencephalograms, we attempted to verify alterations in the functional network as well as the spectral power of neural activities during sleep in RLS patients and to determine whether the changes are reversed by treatment with pramipexole. Twelve drug-naïve RLS patients participated in the study. Overnight polysomnography was performed before and after treatment: the first recording was made immediately prior to administering the first dose of pramipexole, and the second recording was made 12-16 weeks after commencing pramipexole administration. Sixteen age-matched healthy participants served as a control group. The spectral power and interregional phase synchrony were analyzed in 30-s epochs. The functional characteristics of the cortical network were quantified using graph-theory measures. The delta-band power was significantly increased and the small-world network characteristics in the delta band were disrupted in RLS patients compared to the healthy controls. These abnormalities were successfully treated by dopaminergic medication. The delta-band power was significantly correlated with the RLS severity score in the RLS patients prior to treatment. Our findings suggest that the spectral and functional network characteristics of neural activities during sleep become abnormal in RLS patients, and these abnormalities can be successfully treated by a dopamine agonist.
AbstractList The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of treatment with a dopamine agonist. Based on whole-brain electroencephalograms, we attempted to verify alterations in the functional network as well as the spectral power of neural activities during sleep in RLS patients and to determine whether the changes are reversed by treatment with pramipexole. Twelve drug-naïve RLS patients participated in the study. Overnight polysomnography was performed before and after treatment: the first recording was made immediately prior to administering the first dose of pramipexole, and the second recording was made 12-16 weeks after commencing pramipexole administration. Sixteen age-matched healthy participants served as a control group. The spectral power and interregional phase synchrony were analyzed in 30-s epochs. The functional characteristics of the cortical network were quantified using graph-theory measures. The delta-band power was significantly increased and the small-world network characteristics in the delta band were disrupted in RLS patients compared to the healthy controls. These abnormalities were successfully treated by dopaminergic medication. The delta-band power was significantly correlated with the RLS severity score in the RLS patients prior to treatment. Our findings suggest that the spectral and functional network characteristics of neural activities during sleep become abnormal in RLS patients, and these abnormalities can be successfully treated by a dopamine agonist.
Background and Purpose The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of treatment with a dopamine agonist. Based on whole-brain electroencephalograms, we attempted to verify alterations in the functional network as well as the spectral power of neural activities during sleep in RLS patients and to determine whether the changes are reversed by treatment with pramipexole. Methods Twelve drug-naïve RLS patients participated in the study. Overnight polysomnography was performed before and after treatment: the first recording was made immediately prior to administering the first dose of pramipexole, and the second recording was made 12–16 weeks after commencing pramipexole administration. Sixteen age-matched healthy participants served as a control group. The spectral power and interregional phase synchrony were analyzed in 30-s epochs. The functional characteristics of the cortical network were quantified using graph-theory measures. Results The delta-band power was significantly increased and the small-world network characteristics in the delta band were disrupted in RLS patients compared to the healthy controls. These abnormalities were successfully treated by dopaminergic medication. The delta-band power was significantly correlated with the RLS severity score in the RLS patients prior to treatment. Conclusions Our findings suggest that the spectral and functional network characteristics of neural activities during sleep become abnormal in RLS patients, and these abnormalities can be successfully treated by a dopamine agonist. KCI Citation Count: 3
BACKGROUND AND PURPOSEThe purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of treatment with a dopamine agonist. Based on whole-brain electroencephalograms, we attempted to verify alterations in the functional network as well as the spectral power of neural activities during sleep in RLS patients and to determine whether the changes are reversed by treatment with pramipexole. METHODSTwelve drug-naïve RLS patients participated in the study. Overnight polysomnography was performed before and after treatment: the first recording was made immediately prior to administering the first dose of pramipexole, and the second recording was made 12-16 weeks after commencing pramipexole administration. Sixteen age-matched healthy participants served as a control group. The spectral power and interregional phase synchrony were analyzed in 30-s epochs. The functional characteristics of the cortical network were quantified using graph-theory measures. RESULTSThe delta-band power was significantly increased and the small-world network characteristics in the delta band were disrupted in RLS patients compared to the healthy controls. These abnormalities were successfully treated by dopaminergic medication. The delta-band power was significantly correlated with the RLS severity score in the RLS patients prior to treatment. CONCLUSIONSOur findings suggest that the spectral and functional network characteristics of neural activities during sleep become abnormal in RLS patients, and these abnormalities can be successfully treated by a dopamine agonist.
Author Lee, Byeong Uk
Jeong, Min Hee
Choi, Jeong Woo
Cha, Kwang Su
Her, Seong Jin
Kim, Kyung Hwan
Jung, Ki Young
AuthorAffiliation a Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea
b Department of Neurology, Seoul National University College of Medicine, Seoul, Korea
AuthorAffiliation_xml – name: a Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea
– name: b Department of Neurology, Seoul National University College of Medicine, Seoul, Korea
Author_xml – sequence: 1
  givenname: Jeong Woo
  surname: Choi
  fullname: Choi, Jeong Woo
  organization: Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea
– sequence: 2
  givenname: Min Hee
  surname: Jeong
  fullname: Jeong, Min Hee
  organization: Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea
– sequence: 3
  givenname: Seong Jin
  surname: Her
  fullname: Her, Seong Jin
  organization: Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea
– sequence: 4
  givenname: Byeong Uk
  surname: Lee
  fullname: Lee, Byeong Uk
  organization: Department of Neurology, Seoul National University College of Medicine, Seoul, Korea
– sequence: 5
  givenname: Kwang Su
  surname: Cha
  fullname: Cha, Kwang Su
  organization: Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea
– sequence: 6
  givenname: Ki Young
  surname: Jung
  fullname: Jung, Ki Young
  email: jungky10@gmail.com
  organization: Department of Neurology, Seoul National University College of Medicine, Seoul, Korea. jungky10@gmail.com
– sequence: 7
  givenname: Kyung Hwan
  surname: Kim
  fullname: Kim, Kyung Hwan
  email: khkim0604@yonsei.ac.kr
  organization: Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Korea. khkim0604@yonsei.ac.kr
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28831786$$D View this record in MEDLINE/PubMed
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002270708$$DAccess content in National Research Foundation of Korea (NRF)
BookMark eNpVkc1uEzEURi1URNPCA7BBXsIig__G42yQopZCpEhUaVhbHudOxu2MHexJ0bwIz1snKRWs7sLnO_fK3wU688EDQu8pKfhMqc_31heM0KqgvBAFF-QVmjBCymlJKD9DE1pxNZWlkufoIqV7QmRFFH2DzplSnFZKTtCfee1D7E2H7zqAHb6GbjB41Y5D22PjN3jhB4gRti74DN22JgG-G71tY_Ajdh7fmsGBHxL-7YYWryANHaSEl7BNB3ATQw9H07oFFzPwCDFlVT3i67AzvfOA59vgXRrwOoIZ-mx7i143pkvw7nleop83X9dX36fLH98WV_Pl1ArOhylroGaknCkwlS1LkMI0NafcUmobRZUltDG14g2zjEgxE3XDSiGqiouS8UryS_Tp5PWx0Q_W6WDccW6Dfoh6vlovNJOkonSW2S8ndreve9jYfGY0nd5F15s4HpP_v3jXZs-jLmXJJaNZ8PFZEMOvff4o3btkoeuMh7BPOu-gFSVSiozSE2pjSClC87KGEn3oXufu9aF7TbkWOnefMx_-ve8l8bds_gT0da8w
CitedBy_id crossref_primary_10_1016_j_sleep_2019_09_021
crossref_primary_10_1016_j_neubiorev_2021_02_011
crossref_primary_10_1186_s12888_023_05352_0
crossref_primary_10_3390_app11209633
crossref_primary_10_13078_jsm_18015
crossref_primary_10_5664_jcsm_10160
crossref_primary_10_5664_jcsm_10440
crossref_primary_10_1093_sleep_zsac099
crossref_primary_10_1093_sleep_zsac110
crossref_primary_10_3988_jcn_2022_18_3_290
Cites_doi 10.1212/WNL.52.5.938
10.1038/30918
10.1016/j.sleep.2010.08.018
10.1002/mds.22436
10.1038/nature02663
10.1111/j.1600-0404.2006.00669.x
10.1109/TAU.1967.1161901
10.1016/S0167-2789(00)00087-7
10.1371/journal.pone.0077336
10.1523/JNEUROSCI.21-07-02308.2001
10.1056/NEJMcp021288
10.1186/1753-4631-1-3
10.1016/j.schres.2006.06.028
10.1016/S1389-9457(00)00065-4
10.1016/j.neuroimage.2004.10.021
10.1016/j.sleep.2004.01.012
10.1371/journal.pone.0000276
10.1371/journal.pcbi.0030017
10.1016/j.sleep.2006.01.001
10.1016/j.sleep.2005.05.006
10.1385/NI:2:2:145
10.1093/sleep/29.12.1595
10.1016/j.sleep.2004.01.011
10.1016/S1388-2457(03)00137-8
10.1016/j.clinph.2005.08.034
10.1073/pnas.1002570107
10.1093/brain/awt316
10.1002/hbm.20662
10.1016/j.clinph.2005.02.004
10.1016/j.tins.2013.10.002
10.1093/sleep/26.7.819
10.1016/j.clinph.2006.10.021
10.1016/0165-1781(89)90047-4
10.1016/S1389-9457(03)00010-8
10.1016/j.sleep.2014.03.025
10.1523/JNEUROSCI.2015-10.2010
10.1093/sleep/14.6.540
10.1007/s00406-002-0380-7
10.1016/j.brainresbull.2003.09.004
10.1016/j.sleep.2014.03.010
10.1016/0013-4694(81)90225-X
10.1038/nn1758
10.1002/mds.21608
10.1371/journal.pone.0042312
10.1371/journal.pone.0002051
10.1371/journal.pone.0148272
10.1007/s00415-015-7750-3
10.1097/WNF.0b013e3181fd82a1
10.1016/j.sleep.2014.10.025
10.1007/978-1-4615-1079-6_12
10.13078/jsm.15001
10.1016/j.sleep.2009.05.003
10.1212/WNL.52.5.1060
10.1016/S1389-9457(02)00258-7
10.1016/j.neulet.2011.05.030
10.1093/sleep/27.1.147
10.1093/cercor/bhj127
ContentType Journal Article
Copyright Copyright © 2017 Korean Neurological Association
Copyright © 2017 Korean Neurological Association 2017 Korean Neurological Association
Copyright_xml – notice: Copyright © 2017 Korean Neurological Association
– notice: Copyright © 2017 Korean Neurological Association 2017 Korean Neurological Association
DBID NPM
AAYXX
CITATION
7X8
5PM
ACYCR
DOI 10.3988/jcn.2017.13.4.340
DatabaseName PubMed
CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
Korean Citation Index
DatabaseTitle PubMed
CrossRef
MEDLINE - Academic
DatabaseTitleList PubMed

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2005-5013
EndPage 350
ExternalDocumentID oai_kci_go_kr_ARTI_2607119
10_3988_jcn_2017_13_4_340
28831786
Genre Journal Article
GrantInformation_xml – fundername: ;
– fundername: ;
  grantid: 2015R1 D1A1A01056743
– fundername: ;
  grantid: 2014R1A2A2A04003858
GroupedDBID 29K
2WC
5-W
5GY
8JR
8XY
9ZL
AAKDD
ACYCR
ADBBV
ADRAZ
AENEX
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
D-I
DIK
DU5
E3Z
EF.
F5P
GROUPED_DOAJ
HYE
KQ8
M48
M~E
NPM
OK1
PGMZT
RPM
AAYXX
CITATION
7X8
5PM
ID FETCH-LOGICAL-c433t-2feb20598ea7c55e64afb313c11cf818c01fab83f2c206494bf25447734523763
IEDL.DBID RPM
ISSN 1738-6586
IngestDate Tue Nov 21 21:27:01 EST 2023
Tue Sep 17 21:27:09 EDT 2024
Sat Aug 17 01:49:08 EDT 2024
Fri Aug 23 02:18:44 EDT 2024
Sat Sep 28 08:51:05 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords dopamine agonist treatment
spectral power
polysomnography
functional network
restless legs syndrome
delta rhythm
Language English
License Copyright © 2017 Korean Neurological Association
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c433t-2feb20598ea7c55e64afb313c11cf818c01fab83f2c206494bf25447734523763
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
These authors have contributed equally to this work.
https://doi.org/10.3988/jcn.2017.13.4.340
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653621/
PMID 28831786
PQID 1931710664
PQPubID 23479
PageCount 11
ParticipantIDs nrf_kci_oai_kci_go_kr_ARTI_2607119
pubmedcentral_primary_oai_pubmedcentral_nih_gov_5653621
proquest_miscellaneous_1931710664
crossref_primary_10_3988_jcn_2017_13_4_340
pubmed_primary_28831786
PublicationCentury 2000
PublicationDate 2017-10-01
PublicationDateYYYYMMDD 2017-10-01
PublicationDate_xml – month: 10
  year: 2017
  text: 2017-10-01
  day: 01
PublicationDecade 2010
PublicationPlace Korea (South)
PublicationPlace_xml – name: Korea (South)
PublicationTitle Journal of clinical neurology (Seoul, Korea)
PublicationTitleAlternate J Clin Neurol
PublicationYear 2017
Publisher Korean Neurological Association
대한신경과학회
Publisher_xml – name: Korean Neurological Association
– name: 대한신경과학회
References 17908336 - Nonlinear Biomed Phys. 2007 Jul 05;1(1):3
12761367 - N Engl J Med. 2003 May 22;348(21):2103-9
17566123 - Mov Disord. 2007 Sep 15;22(12):1751-6
24204812 - PLoS One. 2013 Oct 28;8(10):e77336
12242580 - Eur Arch Psychiatry Clin Neurosci. 2002 Aug;252(4):185-94
22848757 - PLoS One. 2012;7(7):e42312
14638388 - Brain Res Bull. 2003 Dec 15;62(2):143-50
18937282 - Hum Brain Mapp. 2009 Jul;30(7):2207-19
18446219 - PLoS One. 2008 Apr 30;3(4):e0002051
15670702 - Neuroimage. 2005 Feb 15;24(4):1242-7
19117337 - Mov Disord. 2009 Apr 15;24(5):710-5
10102409 - Neurology. 1999 Mar 23;52(5):938-43
16875801 - Schizophr Res. 2006 Oct;87(1-3):60-6
15222998 - Sleep Med. 2004 Jul;5(4):393-6
21377421 - Sleep Med. 2011 Apr;12(4):416-21
14655914 - Sleep. 2003 Nov 1;26(7):819-21
11438246 - Sleep Med. 2001 Jul;2(4):297-307
16198145 - Sleep Med. 2006 Jan;7(1):25-30
15978488 - Clin Neurophysiol. 2005 Jun;116(6):1265-72
12948792 - Clin Neurophysiol. 2003 Sep;114(9):1638-45
16936722 - Nat Neurosci. 2006 Sep;9(9):1169-76
16459136 - Sleep Med. 2006 Mar;7(2):175-83
25023924 - Sleep Med. 2014 Aug;15(8):860-73
24271324 - Brain. 2014 Jan;137(Pt 1):197-207
11264306 - J Neurosci. 2001 Apr 1;21(7):2308-19
21624430 - Neurosci Lett. 2011 Jul 15;499(1):47-51
26840071 - PLoS One. 2016 Feb 03;11(2):e0148272
20739559 - J Neurosci. 2010 Aug 25;30(34):11379-87
14998252 - Sleep. 2004 Feb 1;27(1):147-50
15184907 - Nature. 2004 Jul 1;430(6995):78-81
17174148 - Clin Neurophysiol. 2007 Feb;118(2):449-56
14592341 - Sleep Med. 2003 Mar;4(2):101-19
15222997 - Sleep Med. 2004 Jul;5(4):385-91
17342210 - PLoS One. 2007 Mar 07;2(3):e276
16796215 - Sleep. 2006 Jun;29(6):770-5
9623998 - Nature. 1998 Jun 4;393(6684):440-2
1798888 - Sleep. 1991 Dec;14(6):540-5
16942543 - Acta Neurol Scand. 2006 Oct;114(4):244-9
15319512 - Neuroinformatics. 2004;2(2):145-62
21060282 - Clin Neuropharmacol. 2010 Nov-Dec;33(6):276-8
16356767 - Clin Neurophysiol. 2006 Feb;117(2):348-68
6165548 - Electroencephalogr Clin Neurophysiol. 1981 May;51(5):483-95
14592342 - Sleep Med. 2003 Mar;4(2):121-32
2748771 - Psychiatry Res. 1989 May;28(2):193-213
19595629 - Sleep Med. 2010 Jan;11(1):75-81
24210928 - Trends Neurosci. 2014 Jan;37(1):10-9
17274684 - PLoS Comput Biol. 2007 Feb 2;3(2):e17
24891078 - Sleep Med. 2014 Jul;15(7):808-15
16452642 - Cereb Cortex. 2007 Jan;17(1):92-9
25929663 - J Neurol. 2015 Jun;262(6):1557-67
20696898 - Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15939-44
25934537 - Sleep Med. 2015 Jun;16(6):703-8
10102429 - Neurology. 1999 Mar 23;52(5):1060-3
Huber (10.3988/jcn.2017.13.4.340_ref39) 2004; 430
Unrath (10.3988/jcn.2017.13.4.340_ref4) 2007; 22
Etgen (10.3988/jcn.2017.13.4.340_ref3) 2005; 24
Watts (10.3988/jcn.2017.13.4.340_ref40) 1998; 393
Sung (10.3988/jcn.2017.13.4.340_ref21) 2008; 14
Olde Dubbelink (10.3988/jcn.2017.13.4.340_ref57) 2014; 137
Leemburg (10.3988/jcn.2017.13.4.340_ref54) 2010; 107
Scalise (10.3988/jcn.2017.13.4.340_ref6) 2004; 5
Spoormaker (10.3988/jcn.2017.13.4.340_ref14) 2010; 30
Earley (10.3988/jcn.2017.13.4.340_ref2) 2003; 348
Ferri (10.3988/jcn.2017.13.4.340_ref13) 2007; 118
Walters (10.3988/jcn.2017.13.4.340_ref23) 2003; 4
Skidmore (10.3988/jcn.2017.13.4.340_ref58) 2011; 499
Sporns (10.3988/jcn.2017.13.4.340_ref30) 2004; 2
Huber (10.3988/jcn.2017.13.4.340_ref42) 2006; 9
Allen (10.3988/jcn.2017.13.4.340_ref1) 2003; 4
Johns (10.3988/jcn.2017.13.4.340_ref19) 1991; 14
Kayser (10.3988/jcn.2017.13.4.340_ref26) 2006; 117
Pearson (10.3988/jcn.2017.13.4.340_ref46) 2006; 7
Luo (10.3988/jcn.2017.13.4.340_ref56) 2015; 262
Stam (10.3988/jcn.2017.13.4.340_ref12) 2007; 1
Jung (10.3988/jcn.2017.13.4.340_ref43) 2015; 12
Scalise (10.3988/jcn.2017.13.4.340_ref33) 2006; 29
Kallweit (10.3988/jcn.2017.13.4.340_ref50) 2010; 33
Schober (10.3988/jcn.2017.13.4.340_ref7) 2004; 27
Allen (10.3988/jcn.2017.13.4.340_ref18) 2014; 15
Scalise (10.3988/jcn.2017.13.4.340_ref10) 2010; 11
Iber (10.3988/jcn.2017.13.4.340_ref24) 2007
Kim (10.3988/jcn.2017.13.4.340_ref45) 2014; 15
Rizzo (10.3988/jcn.2017.13.4.340_ref53) 2009; 24
Buysse (10.3988/jcn.2017.13.4.340_ref22) 1989; 28
Nardone (10.3988/jcn.2017.13.4.340_ref9) 2006; 114
Zucconi (10.3988/jcn.2017.13.4.340_ref25) 2006; 7
Choi (10.3988/jcn.2017.13.4.340_ref47) 2012; 7
Allen (10.3988/jcn.2017.13.4.340_ref8) 2004; 5
Achard (10.3988/jcn.2017.13.4.340_ref59) 2007; 3
Jung (10.3988/jcn.2017.13.4.340_ref44) 2011; 12
Montplaisir (10.3988/jcn.2017.13.4.340_ref48) 1999; 52
Hornyak (10.3988/jcn.2017.13.4.340_ref11) 2005; 116
Mormann (10.3988/jcn.2017.13.4.340_ref28) 2000; 144
Humphries (10.3988/jcn.2017.13.4.340_ref31) 2008; 3
Borbély (10.3988/jcn.2017.13.4.340_ref37) 1981; 51
Bastien (10.3988/jcn.2017.13.4.340_ref20) 2001; 2
Stam (10.3988/jcn.2017.13.4.340_ref17) 2007; 17
Tergau (10.3988/jcn.2017.13.4.340_ref34) 1999; 52
Leistedt (10.3988/jcn.2017.13.4.340_ref15) 2009; 30
Quatrale (10.3988/jcn.2017.13.4.340_ref5) 2003; 114
Göttlich (10.3988/jcn.2017.13.4.340_ref55) 2013; 8
Saletu (10.3988/jcn.2017.13.4.340_ref52) 2002; 252
Micheloyannis (10.3988/jcn.2017.13.4.340_ref16) 2006; 87
Welch (10.3988/jcn.2017.13.4.340_ref27) 1967; 15
Jung (10.3988/jcn.2017.13.4.340_ref51) 2015; 16
Huber (10.3988/jcn.2017.13.4.340_ref38) 2007; 2
Tononi (10.3988/jcn.2017.13.4.340_ref35) 2003; 62
Perrett (10.3988/jcn.2017.13.4.340_ref36) 2001; 21
Choi (10.3988/jcn.2017.13.4.340_ref32) 2016; 11
Sporns (10.3988/jcn.2017.13.4.340_ref29) 2003
Silber (10.3988/jcn.2017.13.4.340_ref49) 2003; 26
Genzel (10.3988/jcn.2017.13.4.340_ref41) 2014; 37
References_xml – volume: 52
  start-page: 938
  year: 1999
  ident: 10.3988/jcn.2017.13.4.340_ref48
  publication-title: Neurology
  doi: 10.1212/WNL.52.5.938
  contributor:
    fullname: Montplaisir
– volume-title: The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref24
  contributor:
    fullname: Iber
– volume: 393
  start-page: 440
  year: 1998
  ident: 10.3988/jcn.2017.13.4.340_ref40
  publication-title: Nature
  doi: 10.1038/30918
  contributor:
    fullname: Watts
– volume: 12
  start-page: 416
  year: 2011
  ident: 10.3988/jcn.2017.13.4.340_ref44
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2010.08.018
  contributor:
    fullname: Jung
– volume: 24
  start-page: 710
  year: 2009
  ident: 10.3988/jcn.2017.13.4.340_ref53
  publication-title: Mov Disord
  doi: 10.1002/mds.22436
  contributor:
    fullname: Rizzo
– volume: 430
  start-page: 78
  year: 2004
  ident: 10.3988/jcn.2017.13.4.340_ref39
  publication-title: Nature
  doi: 10.1038/nature02663
  contributor:
    fullname: Huber
– volume: 114
  start-page: 244
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref9
  publication-title: Acta Neurol Scand
  doi: 10.1111/j.1600-0404.2006.00669.x
  contributor:
    fullname: Nardone
– volume: 15
  start-page: 70
  year: 1967
  ident: 10.3988/jcn.2017.13.4.340_ref27
  publication-title: IEEE Trans Audio Electroacoust
  doi: 10.1109/TAU.1967.1161901
  contributor:
    fullname: Welch
– volume: 144
  start-page: 358
  year: 2000
  ident: 10.3988/jcn.2017.13.4.340_ref28
  publication-title: Physica D: Nonlinear Phenomena
  doi: 10.1016/S0167-2789(00)00087-7
  contributor:
    fullname: Mormann
– volume: 8
  start-page: e77336
  year: 2013
  ident: 10.3988/jcn.2017.13.4.340_ref55
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0077336
  contributor:
    fullname: Göttlich
– volume: 21
  start-page: 2308
  year: 2001
  ident: 10.3988/jcn.2017.13.4.340_ref36
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.21-07-02308.2001
  contributor:
    fullname: Perrett
– volume: 348
  start-page: 2103
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref2
  publication-title: N Engl J Med
  doi: 10.1056/NEJMcp021288
  contributor:
    fullname: Earley
– volume: 1
  start-page: 3
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref12
  publication-title: Nonlinear Biomed Phys
  doi: 10.1186/1753-4631-1-3
  contributor:
    fullname: Stam
– volume: 87
  start-page: 60
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref16
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2006.06.028
  contributor:
    fullname: Micheloyannis
– volume: 2
  start-page: 297
  year: 2001
  ident: 10.3988/jcn.2017.13.4.340_ref20
  publication-title: Sleep Med
  doi: 10.1016/S1389-9457(00)00065-4
  contributor:
    fullname: Bastien
– volume: 24
  start-page: 1242
  year: 2005
  ident: 10.3988/jcn.2017.13.4.340_ref3
  publication-title: Neuroimage
  doi: 10.1016/j.neuroimage.2004.10.021
  contributor:
    fullname: Etgen
– volume: 5
  start-page: 385
  year: 2004
  ident: 10.3988/jcn.2017.13.4.340_ref8
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2004.01.012
  contributor:
    fullname: Allen
– volume: 2
  start-page: e276
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref38
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0000276
  contributor:
    fullname: Huber
– volume: 3
  start-page: e17
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref59
  publication-title: PLoS Comput Biol
  doi: 10.1371/journal.pcbi.0030017
  contributor:
    fullname: Achard
– volume: 7
  start-page: 175
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref25
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2006.01.001
  contributor:
    fullname: Zucconi
– volume: 7
  start-page: 25
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref46
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2005.05.006
  contributor:
    fullname: Pearson
– volume: 2
  start-page: 145
  year: 2004
  ident: 10.3988/jcn.2017.13.4.340_ref30
  publication-title: Neuroinformatics
  doi: 10.1385/NI:2:2:145
  contributor:
    fullname: Sporns
– volume: 29
  start-page: 770
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref33
  publication-title: Sleep
  doi: 10.1093/sleep/29.12.1595
  contributor:
    fullname: Scalise
– volume: 5
  start-page: 393
  year: 2004
  ident: 10.3988/jcn.2017.13.4.340_ref6
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2004.01.011
  contributor:
    fullname: Scalise
– volume: 114
  start-page: 1638
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref5
  publication-title: Clin Neurophysiol
  doi: 10.1016/S1388-2457(03)00137-8
  contributor:
    fullname: Quatrale
– volume: 117
  start-page: 348
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref26
  publication-title: Clin Neurophysiol
  doi: 10.1016/j.clinph.2005.08.034
  contributor:
    fullname: Kayser
– volume: 107
  start-page: 15939
  year: 2010
  ident: 10.3988/jcn.2017.13.4.340_ref54
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1002570107
  contributor:
    fullname: Leemburg
– volume: 137
  start-page: 197
  year: 2014
  ident: 10.3988/jcn.2017.13.4.340_ref57
  publication-title: Brain
  doi: 10.1093/brain/awt316
  contributor:
    fullname: Olde Dubbelink
– volume: 30
  start-page: 2207
  year: 2009
  ident: 10.3988/jcn.2017.13.4.340_ref15
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.20662
  contributor:
    fullname: Leistedt
– volume: 116
  start-page: 1265
  year: 2005
  ident: 10.3988/jcn.2017.13.4.340_ref11
  publication-title: Clin Neurophysiol
  doi: 10.1016/j.clinph.2005.02.004
  contributor:
    fullname: Hornyak
– volume: 37
  start-page: 10
  year: 2014
  ident: 10.3988/jcn.2017.13.4.340_ref41
  publication-title: Trends Neurosci
  doi: 10.1016/j.tins.2013.10.002
  contributor:
    fullname: Genzel
– volume: 26
  start-page: 819
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref49
  publication-title: Sleep
  doi: 10.1093/sleep/26.7.819
  contributor:
    fullname: Silber
– volume: 118
  start-page: 449
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref13
  publication-title: Clin Neurophysiol
  doi: 10.1016/j.clinph.2006.10.021
  contributor:
    fullname: Ferri
– volume: 28
  start-page: 193
  year: 1989
  ident: 10.3988/jcn.2017.13.4.340_ref22
  publication-title: Psychiatry Res
  doi: 10.1016/0165-1781(89)90047-4
  contributor:
    fullname: Buysse
– volume: 4
  start-page: 101
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref1
  publication-title: Sleep Med
  doi: 10.1016/S1389-9457(03)00010-8
  contributor:
    fullname: Allen
– volume: 15
  start-page: 860
  year: 2014
  ident: 10.3988/jcn.2017.13.4.340_ref18
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2014.03.025
  contributor:
    fullname: Allen
– volume: 30
  start-page: 11379
  year: 2010
  ident: 10.3988/jcn.2017.13.4.340_ref14
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.2015-10.2010
  contributor:
    fullname: Spoormaker
– volume: 14
  start-page: 540
  year: 1991
  ident: 10.3988/jcn.2017.13.4.340_ref19
  publication-title: Sleep
  doi: 10.1093/sleep/14.6.540
  contributor:
    fullname: Johns
– volume: 252
  start-page: 185
  year: 2002
  ident: 10.3988/jcn.2017.13.4.340_ref52
  publication-title: Eur Arch Psychiatry Clin Neurosci
  doi: 10.1007/s00406-002-0380-7
  contributor:
    fullname: Saletu
– volume: 62
  start-page: 143
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref35
  publication-title: Brain Res Bull
  doi: 10.1016/j.brainresbull.2003.09.004
  contributor:
    fullname: Tononi
– volume: 15
  start-page: 808
  year: 2014
  ident: 10.3988/jcn.2017.13.4.340_ref45
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2014.03.010
  contributor:
    fullname: Kim
– volume: 51
  start-page: 483
  year: 1981
  ident: 10.3988/jcn.2017.13.4.340_ref37
  publication-title: Electroencephalogr Clin Neurophysiol
  doi: 10.1016/0013-4694(81)90225-X
  contributor:
    fullname: Borbély
– volume: 9
  start-page: 1169
  year: 2006
  ident: 10.3988/jcn.2017.13.4.340_ref42
  publication-title: Nat Neurosci
  doi: 10.1038/nn1758
  contributor:
    fullname: Huber
– volume: 14
  start-page: 201
  year: 2008
  ident: 10.3988/jcn.2017.13.4.340_ref21
  publication-title: J Korean Soc Biol Ther Psychiatry
  contributor:
    fullname: Sung
– volume: 22
  start-page: 1751
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref4
  publication-title: Mov Disord
  doi: 10.1002/mds.21608
  contributor:
    fullname: Unrath
– volume: 7
  start-page: e42312
  year: 2012
  ident: 10.3988/jcn.2017.13.4.340_ref47
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0042312
  contributor:
    fullname: Choi
– volume: 3
  start-page: e0002051
  year: 2008
  ident: 10.3988/jcn.2017.13.4.340_ref31
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0002051
  contributor:
    fullname: Humphries
– volume: 11
  start-page: e0148272
  year: 2016
  ident: 10.3988/jcn.2017.13.4.340_ref32
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0148272
  contributor:
    fullname: Choi
– volume: 262
  start-page: 1557
  year: 2015
  ident: 10.3988/jcn.2017.13.4.340_ref56
  publication-title: J Neurol
  doi: 10.1007/s00415-015-7750-3
  contributor:
    fullname: Luo
– volume: 33
  start-page: 276
  year: 2010
  ident: 10.3988/jcn.2017.13.4.340_ref50
  publication-title: Clin Neuropharmacol
  doi: 10.1097/WNF.0b013e3181fd82a1
  contributor:
    fullname: Kallweit
– volume: 16
  start-page: 703
  year: 2015
  ident: 10.3988/jcn.2017.13.4.340_ref51
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2014.10.025
  contributor:
    fullname: Jung
– start-page: 171
  volume-title: Neuroscience Databases
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref29
  doi: 10.1007/978-1-4615-1079-6_12
  contributor:
    fullname: Sporns
– volume: 12
  start-page: 1
  year: 2015
  ident: 10.3988/jcn.2017.13.4.340_ref43
  publication-title: J Sleep Med
  doi: 10.13078/jsm.15001
  contributor:
    fullname: Jung
– volume: 11
  start-page: 75
  year: 2010
  ident: 10.3988/jcn.2017.13.4.340_ref10
  publication-title: Sleep Med
  doi: 10.1016/j.sleep.2009.05.003
  contributor:
    fullname: Scalise
– volume: 52
  start-page: 1060
  year: 1999
  ident: 10.3988/jcn.2017.13.4.340_ref34
  publication-title: Neurology
  doi: 10.1212/WNL.52.5.1060
  contributor:
    fullname: Tergau
– volume: 4
  start-page: 121
  year: 2003
  ident: 10.3988/jcn.2017.13.4.340_ref23
  publication-title: Sleep Med
  doi: 10.1016/S1389-9457(02)00258-7
  contributor:
    fullname: Walters
– volume: 499
  start-page: 47
  year: 2011
  ident: 10.3988/jcn.2017.13.4.340_ref58
  publication-title: Neurosci Lett
  doi: 10.1016/j.neulet.2011.05.030
  contributor:
    fullname: Skidmore
– volume: 27
  start-page: 147
  year: 2004
  ident: 10.3988/jcn.2017.13.4.340_ref7
  publication-title: Sleep
  doi: 10.1093/sleep/27.1.147
  contributor:
    fullname: Schober
– volume: 17
  start-page: 92
  year: 2007
  ident: 10.3988/jcn.2017.13.4.340_ref17
  publication-title: Cereb Cortex
  doi: 10.1093/cercor/bhj127
  contributor:
    fullname: Stam
SSID ssj0067081
Score 2.1783535
Snippet The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of...
BACKGROUND AND PURPOSEThe purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to...
Background and Purpose The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to...
SourceID nrf
pubmedcentral
proquest
crossref
pubmed
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage 340
SubjectTerms Original
신경과학
SummonAdditionalLinks – databaseName: Scholars Portal Open Access Journals
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1da9swFBVdB2Mvo_v2vtDGngYOkSVL9kMZYV3pxjJKm0DfhCVLSdZU6WIX6j_S37t77SQsIw978oOFZPtI3HN8L-cS8hH74WTGs7gopYwFaIi4SLC_iStdIkph-62J6_CnPBmL7xfpxR5Zt7dafcBqp7TDflLj5bx3-7v5DAf-EBVnDgLul0UjU6Z6jPdEjwtQ8PcTwQVu-KHYJBWk6rc9S5mCMw6BV3ZJzt1TbIWpe2HpdzHQfwsp_4pMxwfk0YpS0kG3Bx6TPReekAfDVdL8KbkbmIDMdE7P585d0yM3rwt6Nm3q6RUtQknbv4LYoQFZOT2dQmCj502w6Jvb0Fmgp535akXxry09c5garir6w00qHNhaHrQzjTDtAAOw1gOmMg09AlF-BY9BB5MFmvTS0bqy_RkZH38dfTmJV-0YYis4r-PEgwoHNpa5Qtk0dVIU3nDGLWPWQ9y3feYLk3Gf2ASITi6MR_8zpbhIsfaGPyf7YRHcS0Jb5lBaJpT0ojAuTzOnHDfMKJWDZorIp_XX19ed64YGtYJQaYBKI1SacS00QBWRD4CPvrQzjV7ZeJ0s9OVSgyL4phM00GN5RN6v4dNwgDArUgS3uKk0MFgGNEtKEZEXHZybNbEVM1OZjIjaAnozABfcvhNm09akG4gycAP26j_WfU0e4gt1JYJvyH69vHFvgerU5l27gf8A5Hj89w
  priority: 102
  providerName: Scholars Portal
Title Abnormal Sleep Delta Rhythm and Interregional Phase Synchrony in Patients with Restless Legs Syndrome and Their Reversal by Dopamine Agonist Treatment
URI https://www.ncbi.nlm.nih.gov/pubmed/28831786
https://search.proquest.com/docview/1931710664
https://pubmed.ncbi.nlm.nih.gov/PMC5653621
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002270708
Volume 13
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
ispartofPNX Journal of Clinical Neurology, 2017, 13(4), , pp.340-350
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV09b9swECXiDEWXIv1WkwZs0amAZFOkRGk0kgZJURdG4gDZCJGibDc2bVjK4D-S39s7ygqSIlMXaRBFUjqS9453fEfIN8yHk-mKhUWZpqEAGyIsYsxvYksbi1KYgSdxHf1Oz6_Fz5vkZo8k3VkYH7Rv9Dxyi2Xk5jMfW7lemn4XJ9Yfj04AhMC6y_o90pOcdyZ6u_ymcuAzkzIJMxnUa9q6MnkOlt4fg4ynTEaMRyLiAtPAYbZdJvEo9SO91HOb6jnI-W_k5CNVdHZAXu0wJB22fX1N9qx7Q16Mdl7yt-R-qB1C0QW9Wli7pqd20RT0crZtZktauJL6bUBMyYAwnI5noMno1dYZJMrd0rmj45Zttaa4TUsvLfqC65r-stMaC3qOA1_TBP0MUACDO6AqvaWnYIUvoRt0OF0hKy-ddKHs78j12Y_JyXm4y78QGsF5E8YVmN0AvzJbSJMkNhVFpTnjhjFTgaI3A1YVOuNVbGJANrnQFRKeSclFgsE2_D3ZdytnPxLqoUJpmJBpJQpt8ySz0nLNtJQ5GEkB-d79fbVuaTYUmCcoNQVSUyg1xbgSCqQWkK8gH3Vr5grJsfE-XanbjQIT4ELFyJjH8oB86cSnYMagG6RwdnVXK4CsDHBVmoqAfGjF-dBmNxoCIp8I-qEANvj0CQxSz8q9G5Sf_vvNQ_ISP7ONFDwi-83mzn4GxNPoY79TANeRyI79aP8LlHgCZw
link.rule.ids 230,315,733,786,790,870,891,2236,24346,27957,27958,53827,53829
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1db5swFLXaTtr2su9u7NOb9jQJEmODw2PUrkq3pIradOqbhY1JsiROFMhD9kP2e3cvhKqt9rI98WBjsDjG53IP5xLyGevhdHTO_DSLY19ADOGnIdY3sZkNRSZMuzJxHZzFvUvx7Sq62iNR8y9MJdo3ehq4-SJw00mlrVwtTKvRibWGgyMgIfDeZa19cg_WayibIL1-AceyXdUmZRLWMmywcZ3M5AnEej8Nep4yGTAeiIALLASH9XaZxJ-pb-xM-26d_4103tVO3tiMTh6TH800ag3KLNiUOjC_7jg8_vM8n5BHO3pKu3XzU7Jn3TNyf7BLwD8nv7vaIcud04u5tSt6bOdlSs8n23KyoKnLaPWFEas9IMOnwwlskvRi6wx68G7p1NFhbeRaUPwCTM8tppmLgvbtuMCOlX1CNdIIUxjQAXUjMJTe0mMI8BdwG7Q7XqLhLx01KvkX5PLk6-io5-9KO_hGcF76YQ4RPTC7jk2liSIbizTXnHHDmMmBQ5g2y1Pd4XloQiBNidA5eqlJyUWEOh5-SA7c0tlXhFYsJDNMyDgXqbZJ1LHScs20lAnEXx750jxWtaodPBREPggHBXBQCAfFuBIK4OCRT_Dg1cxMFfpu43G8VLO1gujiVIVoxscSj3xscKFgMWKGJXV2uSkUsGEGlC2OhUde1ji5vmYDM4_IWwi67oAXvN0CuKgMv3c4eP3fZ34gD3qjQV_1T8--vyEPccq1IPEtOSjXG_sOiFWp31fL6A-EnyKM
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3JbtswECWaFAh66b6oK1v0VECyKVKidTTiGkkbB0biAEEvhEhRtmubNiz54H5Iv7czkhU4QU856SBqIfgovuE8vSHkK9bD6eic-WkWx76AGMJPQ6xvYjMbikyYdmXiOjiPT67Ej-voeq_UVyXaN3oauPkicNNJpa1cLUyr0Ym1hoNjICHw3WWtVZa3DshDmLNh0gTq9Uc4lu2qPimTMJ9hkY3rhCZPIN77bdD3lMmA8UAEXGAxOKy5yyT-UL23Oh24df4_4nlXP7m3IPWfkF9NV2odyizYlDowf-64PN6rr0_J4x1Npd26yTPywLrn5GiwS8S_IH-72iHbndPLubUr2rPzMqUXk205WdDUZbTaacSqD8j06XACiyW93DqDXrxbOnV0WBu6FhR3gumFxXRzUdAzOy6wYWWjUN1phKkMaID6EbiV3tIeBPoLeA3aHS_R-JeOGrX8S3LV_z46PvF3JR58Izgv_TCHyB4YXsem0kSRjUWaa864YczkwCVMm-Wp7vA8NCGQp0ToHD3VpOQiQj0Pf0UO3dLZN4RWbCQzTMg4F6m2SdSx0nLNtJQJxGEe-dYMrVrVTh4KIiCEhAJIKISEYlwJBZDwyBcYfDUzU4X-23gcL9VsrSDKOFUhmvKxxCOfG2womJSYaUmdXW4KBayYAXWLY-GR1zVWbp7ZQM0j8haKbhrgA2-fAWxUxt87LLy995WfyNGw11dnp-c_35FH2ONal_ieHJbrjf0A_KrUH6uZ9A-TESUM
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Abnormal+Sleep+Delta+Rhythm+and+Interregional+Phase+Synchrony+in+Patients+with+Restless+Legs+Syndrome+and+Their+Reversal+by+Dopamine+Agonist+Treatment&rft.jtitle=Journal+of+clinical+neurology+%28Seoul%2C+Korea%29&rft.au=Choi%2C+Jeong+Woo&rft.au=Jeong%2C+Min+Hee&rft.au=Her%2C+Seong+Jin&rft.au=Lee%2C+Byeong+Uk&rft.date=2017-10-01&rft.issn=1738-6586&rft.volume=13&rft.issue=4&rft.spage=340&rft.epage=350&rft_id=info:doi/10.3988%2Fjcn.2017.13.4.340&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1738-6586&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1738-6586&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1738-6586&client=summon