Serum homocysteine, creatinine, and glucose as predictors of the severity and extent of coronary artery disease in asymptomatic members of high-risk families

• Published in: European journal of clinical investigation Vol. 32; no. 7; pp. 472 - 478
• Main Authors: Pajunen, P., Syvänne, M., Nieminen, M. S., Kareinen, A., Viitanen, L., Lehto, S., Laakso, M.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.07.2002; Blackwell
• Subjects: Biological and medical sciences; Biomarkers - blood; Blood Glucose - analysis; Cardiology. Vascular system; Coronary Angiography; coronary disease; Coronary Disease - blood; Coronary Disease - diagnosis; Coronary Disease - etiology; Coronary heart disease; Creatinine - blood; Diabetes Complications; diabetes mellitus; Diabetes Mellitus - blood; Diagnosis, Computer-Assisted; family history; Female; Genetic Predisposition to Disease; Heart; homocysteine; Homocysteine - blood; Humans; Logistic Models; Male; Medical sciences; Middle Aged; Predictive Value of Tests; Risk Factors; Endocrinopathy; Creatinine; Human; High risk; Thiol; Urinary system disease; Diabetes mellitus; Biological marker; Cardiovascular disease; Coronary heart disease; Statistical study; Sulfur containing aminoacid; Homocystein; Severity score; Proteinuria

Background There has been no previous study to determine the severity and extent of coronary artery disease (CAD) in subjects with no diagnosis or symptoms of CAD at the time of the angiography. Methods Fifty‐three subjects, who were siblings of patients with early onset CAD, underwent coronary angi...