The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance - Kim, K A; Park, P W; Hong, S J; Park, J-Y (Clinical pharmacology and therapeutics, 2008)
Keywords: Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases - genetics; Blood Platelets - drug effects; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Resistance - genetics; Female; Genotype; Humans; Korea; Male; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - blood; Platelet Aggregation Inhibitors - pharmacokinetics; Platelet Aggregation Inhibitors - pharmacology; Polymorphism, Genetic; Ticlopidine - administration & dosage; Ticlopidine - analogs & derivatives; Ticlopidine - blood; Ticlopidine - pharmacokinetics; Ticlopidine - pharmacology