Risk factors for vitamin D deficiency and relationship with cardiac biomarkers, inflammation and immune restoration in HIV-infected youth

• Published in: Antiviral therapy Vol. 17; no. 6; pp. 1069 - 1078
• Main Authors: ECKARD, Allison Ross, JUDD, Suzanne E, RIMANN, Nayoka, TANGPRICHA, Vin, MCCOMSEY, Grace A, ZIEGLER, Thomas R, CAMACHO-GONZALEZ, Andres F, FITZPATRICK, Anne M, HADLEY, Graham R, GROSSMANN, Ruth E, SEATON, Lateshia, SEYDAFKAN, Shabnam, MULLIGAN, Mark J
• Format: Journal Article
• Language: English
• Published: London International Medical Press 01.01.2012
• Subjects: Adolescent; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral agents; Biological and medical sciences; Biomarkers - analysis; Body Mass Index; Cardiovascular Diseases - blood; Cardiovascular Diseases - metabolism; Cardiovascular Diseases - pathology; Case-Control Studies; CD4 Lymphocyte Count; Cross-Sectional Studies; Cytokines - blood; Female; HIV - genetics; HIV - pathogenicity; HIV Infections - immunology; HIV Infections - metabolism; HIV Infections - virology; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Inflammation - metabolism; Male; Medical sciences; Motor Activity; Pharmacology. Drug treatments; Prospective Studies; Risk Factors; RNA, Viral - analysis; Sunlight; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D Deficiency - metabolism; Vitamin D Deficiency - pathology; Young Adult; Infection; Heart; Immunopathology; Viral disease; Nutrition disorder; Risk factor; Immune reconstitution; Biological marker; AIDS; Inflammation; Immune deficiency; Nutritional status

Vitamin D deficiency is common in HIV-infected individuals. In adults, traditional and HIV-related factors play a role in vitamin D status, and deficiency appears to impair immune restoration and exacerbate HIV complications, like cardiovascular disease (CVD). This study sought to determine factors...