Use of Cytomegalovirus Immune Globulin to Prevent Cytomegalovirus Disease in Renal-Transplant Recipients

We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease in renal-transplant recipients. Fifty-nine CMV-seronegative patients who received kidneys from donors who had antibodies against CMV were assigned to...

Full description

Saved in:
Bibliographic Details
Published inThe New England journal of medicine Vol. 317; no. 17; pp. 1049 - 1054
Main Authors Snydman, David R, Werner, Barbara G, Heinze-Lacey, Beverly, Berardi, Victor P, Tilney, Nicholas L, Kirkman, Robert L, Milford, Edgar L, Cho, Sang I, Bush, Harry L, Levey, Andrew S, Levey, Raphael H, Strom, Terry B, Carpenter, Charles B, Harmon, William E, Zimmerman, Clarence E, Shapiro, Michael E, Steinman, Theodore, LoGerfo, Frank, Idelson, Beldon, Schröter, Gerhard P.J, Levin, Myron J, McIver, James, Leszczynski, Jeanne, Grady, George F
Format Journal Article
LanguageEnglish
Published Boston, MA Massachusetts Medical Society 22.10.1987
Subjects
Online AccessGet full text

Cover

Loading…
Abstract We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease in renal-transplant recipients. Fifty-nine CMV-seronegative patients who received kidneys from donors who had antibodies against CMV were assigned to receive either intravenous CMV immune globulin or no treatment. The immune globulin was administered in multiple doses over the first four months after transplantation. The incidence of virologically confirmed CMV-associated syndromes was reduced from 60 percent in controls to 21 percent in recipients of CMV immune globulin (P<0.01). Fungal or parasitic superinfections were not seen in globulin recipients but occurred in 20 percent of controls (P = 0.05). Only 4 percent of globulin recipients had marked leukopenia (reflecting serious CMV disease), as compared with 37 percent of the controls (P<0.01). There was a concomitant but not statistically significant reduction in the incidence of CMV pneumonia (17 percent of controls as compared with 4 percent of globulin recipients). A significant reduction in serious CMV-associated disease was observed even when patients were stratified according to therapy for transplant rejection (P = 0.04). We observed no effect of immune globulin on rates of viral isolation or seroconversion, suggesting that treated patients often harbored the virus but that clinically evident disease was much less likely to develop in them. We conclude that CMV immune globulin provides effective prophylaxis in renal-transplant recipients at risk for primary CMV disease. (N Engl J Med 1987; 317: 1049–54.) CYTOMEGALOVIRUS (CMV) is the principal viral pathogen in renal-transplant recipients. 1 It causes serious morbidity, including fever, leukopenia, pneumonia, retinitis, and hepatitis. 2 3 4 5 In addition, CMV disease may be associated with increased mortality and such complications as bacterial, parasitic, or fungal superinfections, and in some studies, graft rejection. 2 3 4 5 CMV-seronegative patients who receive transplants from CMV-seropositive donors represent the group of renal-transplant recipients that is at highest risk for serious CMV disease. 6 , 7 In this population, the risk of CMV-associated morbidity approaches 60 percent. 1 Therefore, efforts have been directed at preventing CMV infection, including the exclusion of antibody-positive donors for antibody-negative recipients, CMV vaccines, . . .
AbstractList We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease in renal-transplant recipients. Fifty-nine CMV-seronegative patients who received kidneys from donors who had antibodies against CMV were assigned to receive either intravenous CMV immune globulin or no treatment. The immune globulin was administered in multiple doses over the first four months after transplantation. The incidence of virologically confirmed CMV-associated syndromes was reduced from 60 percent in controls to 21 percent in recipients of CMV immune globulin (P<0.01). Fungal or parasitic superinfections were not seen in globulin recipients but occurred in 20 percent of controls (P = 0.05). Only 4 percent of globulin recipients had marked leukopenia (reflecting serious CMV disease), as compared with 37 percent of the controls (P<0.01). There was a concomitant but not statistically significant reduction in the incidence of CMV pneumonia (17 percent of controls as compared with 4 percent of globulin recipients). A significant reduction in serious CMV-associated disease was observed even when patients were stratified according to therapy for transplant rejection (P = 0.04). We observed no effect of immune globulin on rates of viral isolation or seroconversion, suggesting that treated patients often harbored the virus but that clinically evident disease was much less likely to develop in them. We conclude that CMV immune globulin provides effective prophylaxis in renal-transplant recipients at risk for primary CMV disease. (N Engl J Med 1987; 317: 1049–54.) CYTOMEGALOVIRUS (CMV) is the principal viral pathogen in renal-transplant recipients. 1 It causes serious morbidity, including fever, leukopenia, pneumonia, retinitis, and hepatitis. 2 3 4 5 In addition, CMV disease may be associated with increased mortality and such complications as bacterial, parasitic, or fungal superinfections, and in some studies, graft rejection. 2 3 4 5 CMV-seronegative patients who receive transplants from CMV-seropositive donors represent the group of renal-transplant recipients that is at highest risk for serious CMV disease. 6 , 7 In this population, the risk of CMV-associated morbidity approaches 60 percent. 1 Therefore, efforts have been directed at preventing CMV infection, including the exclusion of antibody-positive donors for antibody-negative recipients, CMV vaccines, . . .
Abstract We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease in renal-transplant recipients. Fifty-nine CMV-seronegative patients who received kidneys from donors who had antibodies against CMV were assigned to receive either intravenous CMV immune globulin or no treatment. The immune globulin was administered in multiple doses over the first four months after transplantation. The incidence of virologically confirmed CMV-associated syndromes was reduced from 60 percent in controls to 21 percent in recipients of CMV immune globulin (P<0.01). Fungal or parasitic superinfections were not seen in globulin recipients but occurred in 20 percent of controls (P = 0.05). Only 4 percent of globulin recipients had marked leukopenia (reflecting serious CMV disease), as compared with 37 percent of the controls (P<0.01). There was a concomitant but not statistically significant reduction in the incidence of CMV pneumonia (17 percent of controls as compared with 4 percent of globulin recipients). A significant reduction in serious CMV-associated disease was observed even when patients were stratified according to therapy for transplant rejection (P = 0.04). We observed no effect of immune globulin on rates of viral isolation or seroconversion, suggesting that treated patients often harbored the virus but that clinically evident disease was much less likely to develop in them. We conclude that CMV immune globulin provides effective prophylaxis in renal-transplant recipients at risk for primary CMV disease. (N Engl J Med 1987; 317: 1049-54.)
We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease in renal-transplant recipients. Fifty-nine CMV-seronegative patients who received kidneys from donors who had antibodies against CMV were assigned to receive either intravenous CMV immune globulin or no treatment. The immune globulin was administered in multiple doses over the first four months after transplantation. The incidence of virologically confirmed CMV-associated syndromes was reduced from 60 percent in controls to 21 percent in recipients of CMV immune globulin (P less than 0.01). Fungal or parasitic superinfections were not seen in globulin recipients but occurred in 20 percent of controls (P = 0.05). Only 4 percent of globulin recipients had marked leukopenia (reflecting serious CMV disease), as compared with 37 percent of the controls (P less than 0.01). There was a concomitant but not statistically significant reduction in the incidence of CMV pneumonia (17 percent of controls as compared with 4 percent of globulin recipients). A significant reduction in serious CMV-associated disease was observed even when patients were stratified according to therapy for transplant rejection (P = 0.04). We observed no effect of immune globulin on rates of viral isolation or seroconversion, suggesting that treated patients often harbored the virus but that clinically evident disease was much less likely to develop in them. We conclude that CMV immune globulin provides effective prophylaxis in renal-transplant recipients at risk for primary CMV disease.
Author Milford, Edgar L
McIver, James
Bush, Harry L
Shapiro, Michael E
Werner, Barbara G
Cho, Sang I
Snydman, David R
Zimmerman, Clarence E
Idelson, Beldon
Carpenter, Charles B
Levey, Raphael H
Harmon, William E
Grady, George F
Steinman, Theodore
Heinze-Lacey, Beverly
Berardi, Victor P
Tilney, Nicholas L
Kirkman, Robert L
LoGerfo, Frank
Leszczynski, Jeanne
Levey, Andrew S
Strom, Terry B
Schröter, Gerhard P.J
Levin, Myron J
Author_xml – sequence: 1
  givenname: David R
  surname: Snydman
  fullname: Snydman, David R
– sequence: 2
  givenname: Barbara G
  surname: Werner
  fullname: Werner, Barbara G
– sequence: 3
  givenname: Beverly
  surname: Heinze-Lacey
  fullname: Heinze-Lacey, Beverly
– sequence: 4
  givenname: Victor P
  surname: Berardi
  fullname: Berardi, Victor P
– sequence: 5
  givenname: Nicholas L
  surname: Tilney
  fullname: Tilney, Nicholas L
– sequence: 6
  givenname: Robert L
  surname: Kirkman
  fullname: Kirkman, Robert L
– sequence: 7
  givenname: Edgar L
  surname: Milford
  fullname: Milford, Edgar L
– sequence: 8
  givenname: Sang I
  surname: Cho
  fullname: Cho, Sang I
– sequence: 9
  givenname: Harry L
  surname: Bush
  fullname: Bush, Harry L
– sequence: 10
  givenname: Andrew S
  surname: Levey
  fullname: Levey, Andrew S
– sequence: 10
  givenname: Raphael H
  surname: Levey
  fullname: Levey, Raphael H
– sequence: 11
  givenname: Terry B
  surname: Strom
  fullname: Strom, Terry B
– sequence: 12
  givenname: Charles B
  surname: Carpenter
  fullname: Carpenter, Charles B
– sequence: 14
  givenname: William E
  surname: Harmon
  fullname: Harmon, William E
– sequence: 15
  givenname: Clarence E
  surname: Zimmerman
  fullname: Zimmerman, Clarence E
– sequence: 16
  givenname: Michael E
  surname: Shapiro
  fullname: Shapiro, Michael E
– sequence: 17
  givenname: Theodore
  surname: Steinman
  fullname: Steinman, Theodore
– sequence: 18
  givenname: Frank
  surname: LoGerfo
  fullname: LoGerfo, Frank
– sequence: 19
  givenname: Beldon
  surname: Idelson
  fullname: Idelson, Beldon
– sequence: 20
  givenname: Gerhard P.J
  surname: Schröter
  fullname: Schröter, Gerhard P.J
– sequence: 21
  givenname: Myron J
  surname: Levin
  fullname: Levin, Myron J
– sequence: 22
  givenname: James
  surname: McIver
  fullname: McIver, James
– sequence: 23
  givenname: Jeanne
  surname: Leszczynski
  fullname: Leszczynski, Jeanne
– sequence: 24
  givenname: George F
  surname: Grady
  fullname: Grady, George F
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7565338$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/2821397$$D View this record in MEDLINE/PubMed
BookMark eNp9kUtr3DAUhUVJSGfS_oJSMKRkE5zqaUnLMnmTPgjJ2mjsq9aDZU107UD-fRRmyCIp0eYu7neODvfMyc4QByDkC6PHjKrq-6_Tq5_MGs0o54Jppqn4QGZMCVFKSasdMqOUm1JqKz6SOeKK5sek3SN73HAmrJ6Rf3cIRfTF4nGMAf66Pj50acLiMoRpgOK8j8up74ZijMWfBA8wjG_Qkw7BZZdM3cDg-vI2uQHXvcvsDTTdussq_ER2vesRPm_nPrk7O71dXJTXv88vFz-uy0YKPpagDSinc35nl7b17dI5sN4rDaZhSjOrlNVAwTsF0jeSA6uk8d6CaFteiX1yuPFdp3g_AY516LCBPseBOGFtGBU822Tw4BW4ilPK-bFmxkgllTA0U2JDNSkiJvD1OnXBpcea0fq5hfo_LWTV1633tAzQvmi2Z8_7b9u9w8b1Ph-s6fAF06rKJZqMHW2wELAeYBXe_fQJM6SeVw
CODEN NEJMAG
CitedBy_id crossref_primary_10_1016_S1058_9813_05_80002_5
crossref_primary_10_1016_S0022_3476_89_80349_X
crossref_primary_10_1016_S0891_5520_20_30711_X
crossref_primary_10_1097_01_TP_0000148239_00384_F0
crossref_primary_10_1111_tri_12629
crossref_primary_10_1016_S0750_7658_89_80017_6
crossref_primary_10_1111_j_1365_2249_1991_tb05596_x
crossref_primary_10_1016_0011_3840_89_90029_4
crossref_primary_10_1016_S0041_1345_98_00551_X
crossref_primary_10_1016_S0140_6736_87_91306_7
crossref_primary_10_1097_00006454_200205000_00019
crossref_primary_10_1097_00007890_200112270_00013
crossref_primary_10_1111_j_1432_2277_1994_tb01386_x
crossref_primary_10_1016_S0041_1345_01_02920_7
crossref_primary_10_1016_0166_3542_94_90103_1
crossref_primary_10_1016_S1386_6532_00_00061_5
crossref_primary_10_1097_TP_0b013e318224115e
crossref_primary_10_1128_CMR_13_4_602
crossref_primary_10_1016_S0891_5520_05_70043_X
crossref_primary_10_1111_j_1399_3046_2008_00907_x
crossref_primary_10_1007_BF01296422
crossref_primary_10_2165_00019053_200018030_00004
crossref_primary_10_1016_j_transproceed_2011_01_189
crossref_primary_10_1016_S0022_3476_88_80383_4
crossref_primary_10_1046_j_1440_1797_2003_00158_x
crossref_primary_10_1016_S0041_1345_98_00258_9
crossref_primary_10_1097_01_qco_0000136933_67920_dd
crossref_primary_10_1016_S0272_6386_12_81093_6
crossref_primary_10_1016_S0399_077X_05_80265_3
crossref_primary_10_1128_CVI_00037_07
crossref_primary_10_1002_rmv_2017
crossref_primary_10_1016_0924_8579_93_90012_T
crossref_primary_10_1016_0166_3542_92_90046_8
crossref_primary_10_1016_S0891_5520_20_30708_X
crossref_primary_10_1136_bmj_304_6824_416
crossref_primary_10_1007_BF03259312
crossref_primary_10_1034_j_1399_3062_2001_00006_x
crossref_primary_10_1016_S1245_1789_01_72025_2
crossref_primary_10_1128_AAC_02698_15
crossref_primary_10_3390_v6031346
crossref_primary_10_1086_647840
crossref_primary_10_1034_j_1399_3062_2000_020204_x
crossref_primary_10_1097_00006454_199904000_00002
crossref_primary_10_1111_j_1600_6135_2004_00727_x
crossref_primary_10_1016_S0025_6196_12_60725_3
crossref_primary_10_1111_j_1399_6576_1988_tb02838_x
crossref_primary_10_7326_0003_4819_114_7_525
crossref_primary_10_1046_j_1365_2249_2000_01138_x
crossref_primary_10_1056_NEJM199003293221315
crossref_primary_10_1128_AAC_02422_20
crossref_primary_10_1111_j_1399_3038_1994_tb00222_x
crossref_primary_10_1128_JVI_75_19_9177_9186_2001
crossref_primary_10_4049_jimmunol_180_7_4550
crossref_primary_10_1034_j_1399_3062_2001_003001008_x
crossref_primary_10_1016_S0041_1345_96_00141_8
crossref_primary_10_1016_S0272_5231_21_00695_X
crossref_primary_10_1002_j_1875_9114_1992_tb04464_x
crossref_primary_10_1128_JVI_01809_09
crossref_primary_10_1016_S0041_1345_98_00283_8
crossref_primary_10_1016_S0344_0338_11_80704_1
crossref_primary_10_1016_0022_3468_94_90277_1
crossref_primary_10_1034_j_1399_3062_1999_10106_x
crossref_primary_10_1161_01_CIR_91_4_1029
crossref_primary_10_1016_0166_0934_88_90085_7
crossref_primary_10_1056_NEJM198804213181614
crossref_primary_10_3109_00365548909039960
crossref_primary_10_1016_j_jim_2012_09_006
crossref_primary_10_1016_S0889_8561_22_00592_6
crossref_primary_10_1016_0197_1859_88_90069_6
crossref_primary_10_1177_2010105815611811
crossref_primary_10_1111_j_1346_8138_2005_tb00885_x
crossref_primary_10_1111_tid_14183
crossref_primary_10_1016_S1045_1870_97_80056_8
crossref_primary_10_1111_j_1440_1797_2004_00307_x
crossref_primary_10_3390_v10090500
crossref_primary_10_1576_toag_11_2_096_27482
crossref_primary_10_1111_j_1399_3062_2004_00043_x
crossref_primary_10_1136_thx_44_4_241
crossref_primary_10_1128_AAC_01108_17
crossref_primary_10_1034_j_1399_0012_2000_140104_x
crossref_primary_10_1016_S0022_5347_17_32467_9
crossref_primary_10_1002_rmv_309
crossref_primary_10_1111_j_1432_2277_1988_tb01812_x
crossref_primary_10_1086_590934
crossref_primary_10_1097_00007890_200010270_00007
crossref_primary_10_1016_S0163_7258_03_00034_2
crossref_primary_10_1177_088506669701200402
crossref_primary_10_1128_CMR_00034_08
crossref_primary_10_3390_v10080405
crossref_primary_10_1016_0966_842X_96_81503_4
crossref_primary_10_1378_chest_99_3_533
crossref_primary_10_3390_antib2040617
crossref_primary_10_1172_JCI8229
crossref_primary_10_1002_jmv_2189
crossref_primary_10_1111_j_1399_0012_2009_00990_x
crossref_primary_10_1016_S0166_3542_00_00111_X
crossref_primary_10_3109_inf_1991_23_suppl_80_01
crossref_primary_10_1016_0033_0620_91_90028_K
crossref_primary_10_1111_j_1432_2277_1989_tb01846_x
crossref_primary_10_1111_j_1442_200X_1995_tb03301_x
crossref_primary_10_1002_1097_0142_19910915_68_6__1415__AID_CNCR2820681402_3_0_CO_2_0
crossref_primary_10_1002_jmv_1890400306
crossref_primary_10_1517_17425255_2015_988139
crossref_primary_10_1002_j_1875_9114_1991_tb02641_x
crossref_primary_10_1111_j_1399_0012_2008_00942_x
crossref_primary_10_1111_j_1442_2042_1996_tb00325_x
crossref_primary_10_1586_14787210_5_2_295
crossref_primary_10_1097_01_tp_0000209439_27719_ed
crossref_primary_10_1016_0888_0786_88_90001_7
crossref_primary_10_7326_0003_4819_114_7_598
crossref_primary_10_1038_ki_1993_234
crossref_primary_10_2146_ajhp090424
crossref_primary_10_1016_j_pop_2011_07_006
crossref_primary_10_1016_S0272_6386_99_70173_3
crossref_primary_10_1056_NEJM199209173271215
crossref_primary_10_1080_14740338_2019_1662787
crossref_primary_10_1007_BF02417239
crossref_primary_10_2217_imt_09_82
crossref_primary_10_1002_14651858_CD005129_pub2
crossref_primary_10_1016_S1053_2498_02_00648_4
crossref_primary_10_1586_14760584_4_3_381
crossref_primary_10_1016_j_ccm_2005_06_013
crossref_primary_10_1128_CDLI_8_5_859_863_2001
crossref_primary_10_1016_j_transproceed_2015_12_064
crossref_primary_10_1007_BF01311014
crossref_primary_10_1034_j_1399_3062_2000_020102_x
crossref_primary_10_1517_14656566_2_8_1247
crossref_primary_10_3390_life12030361
crossref_primary_10_1016_S0891_5520_20_30706_6
crossref_primary_10_1093_infdis_jiz181
crossref_primary_10_1016_S0891_5520_20_30305_6
crossref_primary_10_1089_088922202753394718
crossref_primary_10_1111_j_1432_2277_1995_tb01535_x
crossref_primary_10_1016_0002_9343_93_90279_X
crossref_primary_10_1016_S0041_1345_98_02035_1
crossref_primary_10_1016_S0399_077X_88_80097_0
crossref_primary_10_1056_NEJM199909163411213
crossref_primary_10_3339_jkspn_2011_15_1_76
crossref_primary_10_3109_00365548909035693
crossref_primary_10_1002_rmv_645
crossref_primary_10_1586_17474124_1_2_287
crossref_primary_10_3947_ic_2024_0016
crossref_primary_10_1007_BF02599140
crossref_primary_10_1016_S0934_8840_11_80093_9
crossref_primary_10_1086_318724
crossref_primary_10_3389_fimmu_2022_680559
crossref_primary_10_1016_j_vaccine_2012_09_056
crossref_primary_10_1016_j_clim_2023_109782
crossref_primary_10_1016_j_idc_2011_07_005
crossref_primary_10_1016_S0065_3101_24_00251_2
crossref_primary_10_3109_08820539309060207
crossref_primary_10_1017_S019594170001763X
crossref_primary_10_1016_0195_6701_91_90039_B
crossref_primary_10_1016_S0891_5520_20_30427_X
crossref_primary_10_1177_019459989210600318
crossref_primary_10_1016_j_transproceed_2006_07_001
crossref_primary_10_3109_00365548909035683
crossref_primary_10_1016_0022_1759_90_90196_3
crossref_primary_10_1016_S0041_1345_01_02668_9
crossref_primary_10_1034_j_1399_3062_1999_010307_x
crossref_primary_10_1007_BF00865477
crossref_primary_10_1097_00007890_200003150_00054
crossref_primary_10_1111_j_1432_2277_1995_tb01491_x
crossref_primary_10_1177_875512259300900405
crossref_primary_10_1002__SICI_1099_1654_199709_7_3_181__AID_RMV200_3_0_CO_2_W
crossref_primary_10_1093_ndt_15_5_711
crossref_primary_10_1016_S0041_1345_96_00161_3
crossref_primary_10_1034_j_1399_3062_2001_003003161_x
crossref_primary_10_1111_vox_12246
crossref_primary_10_1034_j_1600_6143_2003_00074_x
crossref_primary_10_1378_chest_121_2_407
crossref_primary_10_1016_S0399_077X_88_80242_7
crossref_primary_10_1586_eci_12_25
crossref_primary_10_1053_spid_2002_125863
crossref_primary_10_1016_0002_9610_91_91140_E
crossref_primary_10_1056_NEJM198905253202105
crossref_primary_10_1093_infdis_jiz638
crossref_primary_10_1146_annurev_med_48_1_93
crossref_primary_10_1017_S0899823X00086669
crossref_primary_10_7326_0003_4819_116_1_55
crossref_primary_10_1093_jac_45_6_729
crossref_primary_10_1016_j_idc_2014_01_008
crossref_primary_10_2165_00019053_200321070_00002
crossref_primary_10_1007_BF01728886
crossref_primary_10_1590_S0036_46651990000500005
crossref_primary_10_1016_0033_0620_90_90035_Z
crossref_primary_10_1016_S0300_2896_15_31509_X
crossref_primary_10_1007_BF00866315
crossref_primary_10_1086_320902
crossref_primary_10_1034_j_1399_3062_2001_00002_x
crossref_primary_10_1016_0277_5379_89_90088_6
crossref_primary_10_1016_S0065_3101_24_00292_5
crossref_primary_10_1128_IAI_66_7_3179_3182_1998
crossref_primary_10_2139_ssrn_3800383
crossref_primary_10_1111_j_1399_3046_2007_00799_x
crossref_primary_10_1016_S0031_3955_16_38807_1
crossref_primary_10_1016_0045_9380_92_90022_Q
crossref_primary_10_1007_BF00336029
crossref_primary_10_1016_S0039_6109_16_46332_2
crossref_primary_10_1097_00007890_199812270_00019
crossref_primary_10_1111_j_1432_2277_1989_tb01859_x
crossref_primary_10_1007_BF02414602
crossref_primary_10_1016_S0891_5520_20_30342_1
crossref_primary_10_1097_00007890_199707150_00013
crossref_primary_10_1164_ajrccm_143_6_1386
crossref_primary_10_1016_0016_5085_90_90352_2
crossref_primary_10_1016_S0039_6109_16_46443_1
crossref_primary_10_1097_01_TP_0000145989_22373_03
crossref_primary_10_1111_j_1440_1797_2010_01379_x
crossref_primary_10_1128_CMR_00043_19
crossref_primary_10_1111_j_1432_2277_1988_tb01793_x
crossref_primary_10_2307_30142429
crossref_primary_10_1016_S1473_3099_02_00370_5
crossref_primary_10_1002_cpdd_792
crossref_primary_10_1111_tri_1992_5_s1_30
crossref_primary_10_1016_S0065_3101_24_00265_2
crossref_primary_10_1007_s00005_016_0422_x
crossref_primary_10_1016_j_trre_2017_01_001
crossref_primary_10_1172_JCI43961
crossref_primary_10_1128_CMR_13_1_83
crossref_primary_10_1038_5568
crossref_primary_10_1542_pir_28_3_92
crossref_primary_10_1111_j_1399_3062_2012_00773_x
crossref_primary_10_1378_chest_113_4_924
crossref_primary_10_1378_chest_97_2_396
crossref_primary_10_1002_hep_1840160113
crossref_primary_10_1016_S0272_6386_12_81098_5
crossref_primary_10_1016_j_vaccine_2009_09_135
crossref_primary_10_1016_S0002_9343_97_80021_6
crossref_primary_10_1016_S0025_6196_12_60828_3
crossref_primary_10_1016_S1637_5017_06_74518_5
crossref_primary_10_1034_j_1399_3062_2001_00001_x
crossref_primary_10_1056_NEJMoa043337
crossref_primary_10_1007_BF00861569
crossref_primary_10_1097_00007890_200111270_00012
crossref_primary_10_1111_j_1432_2277_1993_tb00742_x
crossref_primary_10_1016_j_mcna_2012_04_002
crossref_primary_10_1007_BF00320227
crossref_primary_10_2165_00063030_200013030_00002
crossref_primary_10_1038_ncomms13627
crossref_primary_10_1007_BF00856544
crossref_primary_10_1093_infdis_jiz428
crossref_primary_10_1007_BF00852868
crossref_primary_10_1007_BF00852867
crossref_primary_10_1016_0735_1097_93_90814_H
crossref_primary_10_1016_0924_8579_94_90050_7
crossref_primary_10_1016_S0889_8561_22_00440_4
crossref_primary_10_1089_hyb_1992_11_569
crossref_primary_10_1007_BF01641421
crossref_primary_10_1016_S0140_6736_97_05535_9
crossref_primary_10_1111_j_1440_1797_2011_01521_x
crossref_primary_10_1046_j_1537_2995_1990_30790385528_x
crossref_primary_10_1097_TP_0000000000001096
crossref_primary_10_1097_01_TP_0000119722_37337_DC
crossref_primary_10_1007_BF00852871
crossref_primary_10_1016_S1473_3099_04_01202_2
crossref_primary_10_1034_j_1399_0012_2000_140303_x
crossref_primary_10_1378_chest_127_1_233
crossref_primary_10_1111_j_1440_1754_1989_tb01437_x
crossref_primary_10_1016_0190_9622_91_70049_8
crossref_primary_10_1093_infdis_jiy229
crossref_primary_10_1097_00007890_200011270_00010
crossref_primary_10_1111_j_1432_2277_1994_tb01384_x
crossref_primary_10_1097_00007890_200209270_00014
crossref_primary_10_1007_BF00336637
crossref_primary_10_3109_08820139709048930
crossref_primary_10_1111_tid_12779
crossref_primary_10_1016_S0272_6386_12_80962_0
crossref_primary_10_1111_j_1749_6632_1993_tb26267_x
crossref_primary_10_1016_j_virusres_2010_10_031
crossref_primary_10_1093_ofid_ofz003
crossref_primary_10_1080_14787210_2017_1328278
crossref_primary_10_1016_S0749_0704_18_30348_8
crossref_primary_10_2217_17460794_1_2_147
crossref_primary_10_1016_S0041_1345_98_00256_5
crossref_primary_10_1016_S0041_1345_02_03892_7
crossref_primary_10_1016_0732_8893_93_90134_S
crossref_primary_10_1111_j_1525_139X_1995_tb00323_x
crossref_primary_10_1016_S0031_3955_05_70096_1
crossref_primary_10_1093_ndt_gfl151
crossref_primary_10_1111_j_1365_3083_1993_tb02591_x
crossref_primary_10_1371_journal_ppat_1005227
crossref_primary_10_1056_NEJM199107183250307
crossref_primary_10_1097_TP_0000000000002191
crossref_primary_10_1007_BF00353829
crossref_primary_10_1371_journal_ppat_1004131
crossref_primary_10_1111_j_1399_0012_2007_00750_x
crossref_primary_10_1097_00007890_199605150_00001
crossref_primary_10_1016_S0955_470X_11_80005_4
crossref_primary_10_1016_S0889_8553_21_00072_8
crossref_primary_10_1016_0039_6257_92_90003_C
crossref_primary_10_2165_00063030_200216020_00002
crossref_primary_10_1111_j_1469_0691_2005_01190_x
crossref_primary_10_1053_trre_2000_16516
crossref_primary_10_1136_jcp_43_5_373
crossref_primary_10_1002_14651858_CD008371_pub2
crossref_primary_10_1378_chest_95_3_627
crossref_primary_10_1592_phco_20_15_1175_34592
crossref_primary_10_1002_jmv_1890410523
crossref_primary_10_1016_S0140_6736_96_90449_3
crossref_primary_10_1016_S0213_005X_11_70054_4
crossref_primary_10_1016_S0954_6111_89_80126_X
crossref_primary_10_1007_s00430_016_0457_y
crossref_primary_10_1097_01_tp_0000204048_90367_97
crossref_primary_10_1007_BF02459326
crossref_primary_10_1111_tid_13960
crossref_primary_10_1128_JVI_00467_12
crossref_primary_10_1053_ajkd_2002_32793
crossref_primary_10_1111_j_1432_2277_1993_tb00665_x
crossref_primary_10_1016_0090_1229_91_90061_E
crossref_primary_10_1097_MOT_0b013e3283186bcf
crossref_primary_10_1016_0002_9610_89_90204_3
crossref_primary_10_1016_S0891_5520_20_30714_5
crossref_primary_10_1097_MOT_0b013e3282435e3f
crossref_primary_10_3390_v14020284
crossref_primary_10_1111_ajt_16725
crossref_primary_10_1086_591533
crossref_primary_10_1128_JVI_73_5_4009_4018_1999
crossref_primary_10_1016_S0891_5520_05_70178_1
crossref_primary_10_1034_j_1399_0012_2000_140409_x
crossref_primary_10_1111_j_1432_2277_1996_tb00888_x
crossref_primary_10_1056_NEJM199009133231103
crossref_primary_10_1097_00007890_199709270_00026
crossref_primary_10_1016_j_transproceed_2004_10_091
crossref_primary_10_1128_JVI_02614_15
crossref_primary_10_1002_jmv_25225
crossref_primary_10_1128_AAC_01794_16
crossref_primary_10_1016_S0889_8588_18_30239_9
crossref_primary_10_1099_vir_0_028738_0
Cites_doi 10.1001/archinte.1977.03630200034012
10.1016/S0140-6736(84)92327-4
10.1097/00007890-197901000-00017
10.7326/0003-4819-91-5-676
10.1056/NEJM198306233082501
10.1016/S0022-3476(81)80662-2
10.7326/0003-4819-106-1-12
10.7326/0003-4819-98-4-442
10.1007/978-1-4684-4073-7
10.1016/S0140-6736(86)91081-0
10.1128/AEM.21.1.84-89.1971
10.1056/NEJM198603273141301
10.1016/S0140-6736(84)90930-9
10.1093/infdis/142.1.9
10.7326/0003-4819-91-5-780
10.1097/00007890-198508000-00010
10.1097/00007890-198411000-00026
10.7326/0003-4819-97-1-11
10.1097/00005792-198007000-00004
10.1097/00007890-198012000-00010
10.1056/NEJM197906143002401
10.1001/jama.1978.03290220058017
10.1056/NEJM198604173141602
10.1093/infdis/148.6.1121
10.1093/infdis/147.6.974
ContentType Journal Article
Copyright 1988 INIST-CNRS
Copyright Massachusetts Medical Society Oct 22, 1987
Copyright_xml – notice: 1988 INIST-CNRS
– notice: Copyright Massachusetts Medical Society Oct 22, 1987
DBID IQODW
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
0TZ
7RV
7X7
7XB
8AO
8C1
8FE
8FH
8FI
ABUWG
AFKRA
AN0
AZQEC
BBNVY
BEC
BENPR
BHPHI
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
GUQSH
HCIFZ
K0Y
LK8
M0R
M0T
M1P
M2M
M2O
M2P
M7P
MBDVC
NAPCQ
PQEST
PQQKQ
PQUKI
PRINS
PSYQQ
Q9U
7X8
DOI 10.1056/NEJM198710223171703
DatabaseName Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Pharma and Biotech Premium PRO
Nursing & Allied Health Database
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
ProQuest Pharma Collection
Public Health Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
ProQuest Central (Alumni)
ProQuest Central
British Nursing Database
ProQuest Central Essentials
Biological Science Collection
eLibrary
ProQuest Central
Natural Science Collection
ProQuest One Community College
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
Research Library Prep
SciTech Premium Collection
New England Journal of Medicine
Biological Sciences
ProQuest Family Health
ProQuest Health Management Database
PML(ProQuest Medical Library)
Psychology Database
Research Library
Science Database (ProQuest)
Biological Science Database
Research Library (Corporate)
Nursing & Allied Health Premium
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest One Psychology
ProQuest Central Basic
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
ProQuest One Psychology
Pharma and Biotech Premium PRO
Research Library Prep
ProQuest Central Student
ProQuest Central Essentials
elibrary
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
New England Journal of Medicine
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central China
ProQuest Central
Health Research Premium Collection
Natural Science Collection
ProQuest Central Korea
Biological Science Collection
ProQuest Research Library
ProQuest Public Health
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest Science Journals
ProQuest Family Health
ProQuest One Academic Eastern Edition
British Nursing Index with Full Text
ProQuest Health Management
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest Psychology Journals
ProQuest One Academic UKI Edition
ProQuest One Academic
MEDLINE - Academic
DatabaseTitleList
ProQuest One Psychology
MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1533-4406
EndPage 1054
ExternalDocumentID 4321476585
10_1056_NEJM198710223171703
2821397
7565338
NJ198710223171703
Genre Original Article
Research Support, U.S. Gov't, P.H.S
Clinical Trial
Randomized Controlled Trial
Journal Article
General Information
GrantInformation_xml – fundername: NIADDK NIH HHS
  grantid: AM31389
– fundername: NCRR NIH HHS
  grantid: RR-00054
GroupedDBID -
08R
0R
0WA
123
1KJ
1VV
2KS
2WC
3O-
3V.
4
4.4
53G
55
5D0
5RE
7FN
7RV
7X7
85S
8AO
8C1
8FE
8FH
8FI
8RP
8WZ
A6W
AACLI
AAIKC
AALRV
AAPBV
AAQQT
AARDX
AASXA
AAWTL
ABACO
ABEHJ
ABFLS
ABIVO
ABOCM
ABPPZ
ABPTK
ABQIJ
ABUFD
ABUWG
ABWJO
ACGFS
ACGOD
ACJLH
ACNCT
ACPRK
ACVYA
ADBBV
ADCBC
AENEX
AETEA
AFDAS
AFFNX
AFKRA
AFMIJ
AGNAY
AHMBA
AJYGW
ALMA_UNASSIGNED_HOLDINGS
AN0
AQUVI
AZQEC
BBAFP
BBNVY
BCU
BENPR
BHPHI
BKEYQ
BKNYI
BNQBC
BPHCQ
BVXVI
CJ0
CS3
DCD
DU5
DWQXO
DZ
EBS
EJD
ET
F5P
FA8
FD8
FM.
FYUFA
G8K
GJ
GNUQQ
GUQSH
HCIFZ
HZ
IH2
J5H
K78
KM
KOO
L7B
LK8
M0R
M0T
M1P
M2M
M2O
M2P
M7P
MBDVC
MVM
N9A
NEJ
NHB
O9-
OHM
OHT
OMK
OVD
P-O
P2P
PADUT
PQEST
PQQKQ
PQUKI
PRINS
PROAC
PSQYO
QZG
RHI
RWL
RXW
S6N
SJFOW
SJN
TAE
TAF
TN5
TWZ
U1N
UBX
UCV
UHB
UKR
VQA
W2G
WH7
X
X7M
XFK
XJT
XZL
YCJ
YHZ
YNT
YQJ
YYQ
YZZ
ZA5
ZGI
ZHY
ZKB
ZXP
---
-DZ
-ET
-~X
.-4
.55
.CO
.GJ
0R~
186
1CY
29N
34G
36B
39C
41~
68V
6TJ
9M8
AAEJM
AAJWC
AAMNW
AAUGY
AAUTI
AAYOK
ABCQX
ABEFU
ACKOT
ACPFK
ACPVT
ACRZS
ACTDY
ADRHT
AFFDN
AFHKK
AFOSN
AGFXO
AGHSJ
AJJEV
AJUXI
AKALU
C45
CCPQU
D0S
EX3
F20
H13
HF~
HZ~
I4R
IQODW
K-O
MQT
N4W
NAPCQ
OK1
PCD
PSYQQ
QJJ
S10
SKT
TEORI
TUQ
UKHRP
UMD
UQL
WHG
WOQ
WOW
XOL
XYN
YFH
YQI
YR2
YRY
YYP
ZCA
ZR0
ZVN
~KM
ABBLC
ABJNI
ADUKH
ALIPV
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
ABDPE
CITATION
HMCUK
0TZ
7XB
BEC
K0Y
Q9U
7X8
ID FETCH-LOGICAL-c432t-e78e5a7440a9b9dfdbaae9ff57e8c157195597e0efa5e4fc42e1648ff9e3dd263
IEDL.DBID 8C1
ISSN 0028-4793
IngestDate Wed Dec 04 09:09:48 EST 2024
Tue Nov 19 04:31:03 EST 2024
Thu Nov 21 23:43:27 EST 2024
Sat Sep 28 07:29:07 EDT 2024
Sun Oct 29 17:09:43 EDT 2023
Wed Nov 11 00:36:28 EST 2020
IsPeerReviewed true
IsScholarly true
Issue 17
Keywords Virus
Human
Infection
Prevention
Cytomegalovirus
Urinary system disease
Herpesviridae
Surgery
Immunotherapy
Homotransplantation
Betaherpesvirinae
Kidney
Language English
License CC BY 4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c432t-e78e5a7440a9b9dfdbaae9ff57e8c157195597e0efa5e4fc42e1648ff9e3dd263
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
PMID 2821397
PQID 1884545380
PQPubID 40644
PageCount 6
ParticipantIDs proquest_miscellaneous_81032719
proquest_journals_1884545380
crossref_primary_10_1056_NEJM198710223171703
pubmed_primary_2821397
pascalfrancis_primary_7565338
mms_nejm_10_1056_NEJM198710223171703
ProviderPackageCode DCD
7FN
PublicationCentury 1900
PublicationDate 1987-10-22
PublicationDateYYYYMMDD 1987-10-22
PublicationDate_xml – month: 10
  year: 1987
  text: 1987-10-22
  day: 22
PublicationDecade 1980
PublicationPlace Boston, MA
PublicationPlace_xml – name: Boston, MA
– name: United States
– name: Boston
PublicationTitle The New England journal of medicine
PublicationTitleAlternate N Engl J Med
PublicationYear 1987
Publisher Massachusetts Medical Society
Publisher_xml – name: Massachusetts Medical Society
References Suwansirikul (r005) 1977; 137
Winston (r020) 1982; 97
Peterson (r032) 1983; 148
Glazer (r009) 1979; 91
r001
Pass (r011) 1980; 142
r023
r017
Fryd (r004) 1980; 30
Hirsch (r014) 1983; 308
Chatterjee (r003) 1978; 240
Collaborative DHPG Treatment Study Group (r016) 1986; 314
Cheeseman (r013) 1979; 300
Yeager (r018) 1981; 98
Betts (r008) 1979; 91
Preiksaitis (r012) 1983; 147
Winston (r033) 1987; 106
Peterson (r002) 1980; 59
Meyers (r019) 1983; 98
O'Reilly (r021) 1983; 15
r034
r006
r028
(r031) 1986; 35
Plotkin (r010) 1984; 1
r026
Bernstein (r029) 1971; 21
r027
Kramer (r015) 1984; 1
Snydman (r025) 1984; 38
Weiland (r030) 1986; 1
Zaia (r024) 1979; 27
Bowden (r022) 1986; 314
Smiley (r007) 1985; 40
References_xml – volume: 137
  start-page: 1026
  year: 1977
  ident: r005
  publication-title: Arch Intern Med
  doi: 10.1001/archinte.1977.03630200034012
  contributor:
    fullname: Suwansirikul
– volume: 1
  start-page: 989
  year: 1984
  ident: r015
  publication-title: Lancet
  doi: 10.1016/S0140-6736(84)92327-4
  contributor:
    fullname: Kramer
– ident: r034
– volume: 27
  start-page: 66
  year: 1979
  ident: r024
  publication-title: Transplantation
  doi: 10.1097/00007890-197901000-00017
  contributor:
    fullname: Zaia
– volume: 91
  start-page: 676
  year: 1979
  ident: r009
  publication-title: Ann Intern Med
  doi: 10.7326/0003-4819-91-5-676
  contributor:
    fullname: Glazer
– volume: 308
  start-page: 1489
  year: 1983
  ident: r014
  publication-title: N Engl J Med
  doi: 10.1056/NEJM198306233082501
  contributor:
    fullname: Hirsch
– volume: 98
  start-page: 281
  year: 1981
  ident: r018
  publication-title: J Pediatr
  doi: 10.1016/S0022-3476(81)80662-2
  contributor:
    fullname: Yeager
– ident: r026
– volume: 106
  start-page: 12
  year: 1987
  ident: r033
  publication-title: Ann Intern Med
  doi: 10.7326/0003-4819-106-1-12
  contributor:
    fullname: Winston
– ident: r028
– volume: 98
  start-page: 442
  year: 1983
  ident: r019
  publication-title: Ann Intern Med
  doi: 10.7326/0003-4819-98-4-442
  contributor:
    fullname: Meyers
– ident: r001
  doi: 10.1007/978-1-4684-4073-7
– volume: 1
  start-page: 976
  year: 1986
  ident: r030
  publication-title: Lancet
  doi: 10.1016/S0140-6736(86)91081-0
  contributor:
    fullname: Weiland
– volume: 21
  start-page: 84
  year: 1971
  ident: r029
  publication-title: Appl Microbiol
  doi: 10.1128/AEM.21.1.84-89.1971
  contributor:
    fullname: Bernstein
– ident: r017
– volume: 314
  start-page: 801
  year: 1986
  ident: r016
  publication-title: N Engl J Med
  doi: 10.1056/NEJM198603273141301
  contributor:
    fullname: Collaborative DHPG Treatment Study Group
– volume: 1
  start-page: 528
  year: 1984
  ident: r010
  publication-title: Lancet
  doi: 10.1016/S0140-6736(84)90930-9
  contributor:
    fullname: Plotkin
– volume: 142
  start-page: 9
  year: 1980
  ident: r011
  publication-title: J Infect Dis
  doi: 10.1093/infdis/142.1.9
  contributor:
    fullname: Pass
– volume: 91
  start-page: 780
  year: 1979
  ident: r008
  publication-title: Ann Intern Med
  doi: 10.7326/0003-4819-91-5-780
  contributor:
    fullname: Betts
– ident: r027
– ident: r006
– volume: 40
  start-page: 157
  year: 1985
  ident: r007
  publication-title: Transplantation
  doi: 10.1097/00007890-198508000-00010
  contributor:
    fullname: Smiley
– ident: r023
– volume: 38
  start-page: 553
  year: 1984
  ident: r025
  publication-title: Transplantation
  doi: 10.1097/00007890-198411000-00026
  contributor:
    fullname: Snydman
– volume: 97
  start-page: 11
  year: 1982
  ident: r020
  publication-title: Ann Intern Med
  doi: 10.7326/0003-4819-97-1-11
  contributor:
    fullname: Winston
– volume: 59
  start-page: 283
  year: 1980
  ident: r002
  publication-title: Medicine (Baltimore)
  doi: 10.1097/00005792-198007000-00004
  contributor:
    fullname: Peterson
– volume: 30
  start-page: 436
  year: 1980
  ident: r004
  publication-title: Transplantation
  doi: 10.1097/00007890-198012000-00010
  contributor:
    fullname: Fryd
– volume: 300
  start-page: 1345
  year: 1979
  ident: r013
  publication-title: N Engl J Med
  doi: 10.1056/NEJM197906143002401
  contributor:
    fullname: Cheeseman
– volume: 35
  start-page: 231
  year: 1986
  ident: r031
  publication-title: MMWR
– volume: 240
  start-page: 2446
  year: 1978
  ident: r003
  publication-title: JAMA
  doi: 10.1001/jama.1978.03290220058017
  contributor:
    fullname: Chatterjee
– volume: 314
  start-page: 1006
  year: 1986
  ident: r022
  publication-title: N Engl J Med
  doi: 10.1056/NEJM198604173141602
  contributor:
    fullname: Bowden
– volume: 148
  start-page: 1121
  year: 1983
  ident: r032
  publication-title: J Infect Dis
  doi: 10.1093/infdis/148.6.1121
  contributor:
    fullname: Peterson
– volume: 15
  start-page: 1405
  year: 1983
  ident: r021
  publication-title: Transplant Proc
  contributor:
    fullname: O'Reilly
– volume: 147
  start-page: 974
  year: 1983
  ident: r012
  publication-title: J Infect Dis
  doi: 10.1093/infdis/147.6.974
  contributor:
    fullname: Preiksaitis
SSID ssj0000149
Score 1.8346559
Snippet We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease in...
Abstract We undertook a prospective randomized trial to examine whether an intravenous cytomegalovirus (CMV) immune globulin would prevent primary CMV disease...
SourceID proquest
crossref
pubmed
pascalfrancis
mms
SourceType Aggregation Database
Index Database
Publisher
StartPage 1049
SubjectTerms Adult
Biological and medical sciences
Clinical Trials as Topic
Cytomegalovirus
Cytomegalovirus - immunology
Cytomegalovirus Infections - prevention & control
Female
Humans
Immunization, Passive - adverse effects
Immunization, Passive - methods
Immunoglobulins - administration & dosage
Infections
Investigations
Kidney Transplantation
Laboratories
Male
Medical sciences
Mycoses - prevention & control
Parasitic Diseases - prevention & control
Postoperative Complications - prevention & control
Prospective Studies
Random Allocation
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Transplants & implants
Title Use of Cytomegalovirus Immune Globulin to Prevent Cytomegalovirus Disease in Renal-Transplant Recipients
URI http://dx.doi.org/10.1056/NEJM198710223171703
https://www.ncbi.nlm.nih.gov/pubmed/2821397
https://www.proquest.com/docview/1884545380
https://search.proquest.com/docview/81032719
Volume 317
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9QwDLe4TUK8oPExUdiOPOyRape2adInxG6bBtImNHHSvVVJ44hNXHusPST-e-I2PYaAvfShjdzWTmI7tn8GOKqk5UbqWYzCmTjL_MVUPI2N5UqqSrnEUHHy5VV-scg-LcUyHLi1Ia1y3BP7jdo2FZ2RH3OlMq_tUzV7v_4eU9coiq6GFhoT2OWk6KhSfM7vwUcF8zecII2oQyI_pk7z5G-Tw-NVKJdj16ygmSarVUt5krr1rHJDj4v_G6G9Mjrfg6fBimQfBrE_g0dYP4fHlyFO_gK-LlpkjWPzn12zQq8Emh83d5uWfaRqEGSUYkEZ6KxrWMBw-mvo6RC5YX7UNfqXxQMM-jcvCX-jullTIWX7EhbnZ1_mF3HoqRBXWZp0MUqFQhMqoC5MYZ01WmPhnJCoKi4k7xHpcIZOC8xclSXoHSrlXIGptUme7sNO3dT4CtjMcics4bmnnpwoNEqO3OSFFdbKJIvg3cjPcj1AZ5R9yFvk5T_YH8GR53lZ4-3q4WGHfwhlS1p609T72xEcjEIqw3Jsy9-TJ4K328d-IVF0RNfYbNpSEbSg__8I9gfRbil7r5Ts5NcPU34DT-hTSa8lyQHsdHcbPPQGS2emMJFLOe3n5hR2T86uPl__Aq1F6Gg
link.rule.ids 314,780,784,12056,12223,21388,27924,27925,31719,31720,33266,33267,33744,33745,43310,43579,43805,73745,74014,74302
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB7RrQRcEK-KlJb60CNR10kcOycEpdUWuitUdaXeIjseq0Vssm2ySPx7PBtnAQG95JBYk2TG9jz9DcBhJS03Uo9jFM7EWeYvpuJpbCxXUlXKJYYOJ09n-WSefboSVyHg1oayymFPXG_UtqkoRn7Elcq8tk_V-N3yNqauUZRdDS00tmCbkNPFCLY_nMy-XPwGIBUM4BBDGnCHRH5EvebJ4yaXxytRLoe-WUE3bS0WLVVK6tYzy_VdLv5vhq7V0elTeBLsSPa-F_wzeID1c3g4DZnyF3A9b5E1jh3_6JoFejXQfL-5W7XsjM6DIKMiC6pBZ13DAorTX0M_9rkb5kddoH9Z3AOhf_Oy8DeqmyUdpWxfwvz05PJ4EoeuCnGVpUkXo1QoNOEC6sIU1lmjNRbOCYmq4kLyNSYdjtFpgZmrsgS9S6WcKzC1NsnTHRjVTY2vgI0td8ISonvqyYlCo-TITV5YYa1MsgjeDvwslz14RrlOeou8_Af7Izj0PC9r_Lq4f9j-H0LZkJbeOPUedwR7g5DKsCDb8tf0ieBg89gvJcqP6BqbVVsqAhf0_x_BTi_aDWXvl5KlvHs_5QN4NLmcnpfnZ7PPr-ExfTZpuSTZg1F3t8J9b7505k2Yoz8BTLHqdQ
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT9wwDLfGIaG9TOwDrQNGH3hcdU3bNOnTxIATbOOE0E7irWobRzDt2oP2Ju2_n31Nb6BtvPShjdzWdmI7dn4GOKyUEaUqwgClLYMkoUtZiTgojdBKV9pGJR9OvpimZ7Pk87W8dvVPrSurHNbE1UJtmor3yMdC64SsfazDsXVlEZcnk4-Lu4A7SHGm1bXT2IBNsophNILNT6fTy6sHYFLOGXb7SQMGkUzH3Heeo28Of8igCjX00HJ2amM-b7lqsmiJcbbvePF_l3Rlmibb8ML5lP5RrwQv4RnWr2DrwmXNX8PNrEW_sf7xr66ZI5mE5uft_bL1z_lsCPpccMH16H7X-A7R6a-hJ30ex6dRV0gvC3pQ9B8kF7pR3S74WGX7BmaT02_HZ4HrsBBUSRx1ASqNsmCMwCIrM2NNWRSYWSsV6kpIJVb4dBiiLSQmtkoipPBKW5thbEyUxjswqpsa34IfGmGlYXT3mMjJrEAlUJRpZqQxKko8-DDwM1_0QBr5KgEu0_wf7PfgkHie1_h9_vSw_UdCWZNW5KhS9O3B3iCk3E3ONv-jSh4crB_TtOJcSVFjs2xzzUCD9P8e7PSiXVOmGJW95ndPUz6ALVLP_Ov59MsuPOevZoMXRXsw6u6XuE-eTFe-dyr6G2W27qI
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Use+of+Cytomegalovirus+Immune+Globulin+to+Prevent+Cytomegalovirus+Disease+in+Renal-Transplant+Recipients&rft.jtitle=The+New+England+journal+of+medicine&rft.au=Snydman%2C+David+R&rft.au=Werner%2C+Barbara+G&rft.au=Heinze-Lacey%2C+Beverly&rft.au=Berardi%2C+Victor+P&rft.date=1987-10-22&rft.pub=Massachusetts+Medical+Society&rft.issn=0028-4793&rft.eissn=1533-4406&rft.volume=317&rft.issue=17&rft.spage=1049&rft_id=info:doi/10.1056%2FNEJM198710223171703&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=4321476585
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0028-4793&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0028-4793&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0028-4793&client=summon