Red wine activates plasma membrane redox system in human erythrocytes

• Published in: Free radical research Vol. 50; no. 5; pp. 557 - 569
• Main Authors: Tedesco, Idolo, Moccia, Stefania, Volpe, Silvestro, Alfieri, Giovanna, Strollo, Daniela, Bilotto, Stefania, Spagnuolo, Carmela, Di Renzo, Massimo, Aquino, Rita P., Russo, Gian Luigi
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 03.05.2016
• Subjects: Anthocyanins; Anthocyanins - chemistry; Anthocyanins - metabolism; Antioxidants - administration & dosage; Antioxidants - analysis; Antioxidants - metabolism; chloramines; Chloramines - chemistry; Chloramines - metabolism; Erythrocyte Membrane - drug effects; Erythrocyte Membrane - metabolism; erythrocytes; Erythrocytes - drug effects; Erythrocytes - metabolism; GSH; Humans; Oxidation-Reduction; Oxidative Stress - drug effects; Plasma Membrane Redox System; Polyphenols - chemistry; Polyphenols - metabolism; Quercetin - chemistry; Quercetin - metabolism; red wine; Wine - analysis; Anthocyanins; red wine; erythrocytes; GSH; Plasma Membrane Redox System; chloramines

In the present study, we report that polyphenols present in red wine obtained by a controlled microvinification process are able to protect human erythrocytes from oxidative stress and to activate Plasma Membrane Redox System (PMRS). Human plasma obtained from healthy subjects was incubated in the p...