Platelet function after cardiac surgery and its association with severe postoperative bleeding: the PLATFORM study

• Published in: Platelets (Edinburgh) Vol. 30; no. 7; pp. 908 - 914
• Main Authors: Ranucci, Marco, Pistuddi, Valeria, Di Dedda, Umberto, Menicanti, Lorenzo, De Vincentiis, Carlo, Baryshnikova, Ekaterina
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 03.10.2019; Taylor & Francis Group
• Subjects: Aged; Bleeding; cardiac; Cardiac Surgical Procedures - methods; Cohort Studies; Female; Humans; Male; Middle Aged; platelet function tests; Platelet Function Tests - methods; Postoperative Hemorrhage - blood; Prospective Studies; surgery; platelet function tests; Bleeding; cardiac; surgery

Platelet dysfunction after cardiac surgery is a determinant of postoperative bleeding. The existing guidelines suggest the use of desmopressin and/or platelet concentrate transfusions in case of platelet dysfunction in bleeding patients, but no cut-off values for platelet activity exist in the liter...