Antifungal Susceptibility of Oral Candida Isolates from Mother-Infant Dyads to Nystatin, Fluconazole, and Caspofungin

• Published in: Journal of fungi (Basel) Vol. 9; no. 5; p. 580
• Main Authors: Alkhars, Naemah, Gaca, Anthony, Zeng, Yan, Al-Jallad, Nisreen, Rustchenko, Elena, Wu, Tong Tong, Eliav, Eli, Xiao, Jin
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 17.05.2023; MDPI
• Subjects: antifungal agent; Antifungal agents; Biofilms; Candida; Caspofungin; CDR2 gene; Children; Children & youth; Clinical isolates; Complementarity-determining region 1; Dental caries; Drugs; Enzymes; Fluconazole; Fungi; Genomes; in vitro susceptibility; Infants; Laboratories; MDR1 protein; Minimum inhibitory concentration; Missense mutation; Mothers; Mutation; Nystatin; oral Candida; Susceptibility; Whole genome sequencing; Yeast; United States > US; antifungal agent; fluconazole; in vitro susceptibility; oral Candida; nystatin; caspofungin

The carriage of in children's oral cavities is associated with a higher risk for early childhood caries, so controlling this fungus in early life is essential for preventing caries. In a prospective cohort of 41 mothers and their children from 0 to 2 years of age, this study addressed four main...