Object recognition analysis in mice using nose-point digital video tracking

• Published in: Journal of neuroscience methods Vol. 168; no. 2; pp. 422 - 430
• Main Authors: Benice, T.S., Raber, Jacob
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.03.2008
• Subjects: Animals; Apolipoprotein E; Apolipoproteins E - genetics; Automation; Behavior, Animal - physiology; Data Interpretation, Statistical; Form Perception - physiology; Genotype; Male; Mice; Mice, Inbred C57BL; Novel location; Novel object; Psychomotor Performance - physiology; Recognition (Psychology) - physiology; Rodent behavior; Video tracking; Videodisc Recording - methods; Novel location; Rodent behavior; Automation; Video tracking; NO/NL; NPVT; Apolipoprotein E; ICC; Novel object

Preferential exploration of novel locations and objects by rodents has been used to test the effects of various manipulations on object recognition memory. However, manual scoring is time-consuming, requires extensive training, and is subject to inter-observer variability. Since rodents explore prim...