N-heterocyclic carbene catalyzed additions of 3-trimethylsilyl propiolate to aldehydes

• Published in: Journal of Saudi Chemical Society Vol. 20; no. 2; pp. 207 - 212
• Main Authors: Du, Guang-Fen, Zou, Xiao-Lei, Dai, Bin, He, Lin
• Format: Journal Article
• Language: English
• Published: Riyadh, Saudi Arabia Elsevier B.V 01.03.2016; Saudi Chemical Society; Elsevier
• Subjects: 3-Trimethylsilyl propiolate; Alkynylation; N-heterocyclic carbenes; β-Branched Morita–Baylis–Hillman adducts; Alkynylation; 3-Trimethylsilyl propiolate; β-Branched Morita–Baylis–Hillman adducts; N-heterocyclic carbenes

A N-heterocyclic carbene (NHC) catalyzed addition reaction of 3-trimethylsilyl propiolate with aldehydes has been developed. Under the catalysis of 2mol% NHCs, benzaldehyde, furfural, β-naphthaldehyde, meta- and para-substituted aromatic aldehydes reacted with 3-trimethylsilyl propiolate to afford β...