Retinal Circular RNA hsa_circ_0087207 Expression Promotes Apoptotic Cell Death in Induced Pluripotent Stem Cell-Derived Leber’s Hereditary Optic Neuropathy-like Models - Yang, Yi-Ping; Chang, Yuh-Lih; Lai, Yun-Hsien; Tsai, Ping-Hsing; Hsiao, Yu-Jer; Nguyen, Long Hoang; Lim, Xue-Zhen; Weng, Chang-Chi; Ko, Yu-Ling; Yang, Chang-Hao; Hwang, De-Kuang; Chen, Shih-Jen; et al. (Biomedicines, 2022)
Keywords: Amino acids; Apoptosis; Bioinformatics; Blood cells; Cell cycle; Cell death; Circular RNA; Degeneration; Disease; Gene expression; Genotypes; hsa_circ_0087207; induced pluripotent stem cells; Inhibitory postsynaptic potentials; Kinases; Leber’s hereditary optic neuropathy; Mitochondria; Mitochondrial DNA; Mutation; Next-generation sequencing; Optic neuropathy; Patients; Peripheral blood; Phenotypes; Pluripotency; Reactive oxygen species; Retina; Retinal ganglion cells; Review boards; Stem cells; unaffected carrier; United Kingdom--UK; United States--US; unaffected carrier; hsa_circ_0087207; Leber’s hereditary optic neuropathy; induced pluripotent stem cells; retinal ganglion cells