Pancreas Transplantation in C-Peptide Positive Patients: Does “Type” of Diabetes Really Matter?

• Published in: Journal of the American College of Surgeons Vol. 220; no. 4; pp. 716 - 727
• Main Authors: Stratta, Robert J., MD, FACS, Rogers, Jeffrey, MD, FACS, Farney, Alan C., MD, PhD, Orlando, Giuseppe, MD, PhD, El-Hennawy, Hany, MD, Gautreaux, Michael D., PhD, Reeves-Daniel, Amber, DO, Palanisamy, Amudha, MD, Iskandar, Samy S., MBBCh, PhD, Bodner, Jason K., MMS, PA-C
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2015
• Subjects: Adult; Biomarkers - blood; C-Peptide - blood; Diabetes Mellitus - blood; Diabetes Mellitus - mortality; Diabetes Mellitus - surgery; Disease Progression; Female; Follow-Up Studies; Graft Survival; Humans; Male; North Carolina - epidemiology; Pancreas Transplantation - methods; Preoperative Period; Prognosis; Retrospective Studies; Surgery; Survival Rate - trends; North Carolina; ESRD; SPKT; T1DM; type 1 diabetes mellitus; T2DM; body mass index; IPTR; DM; diabetes mellitus; pancreas transplantation; end-stage renal disease; simultaneous pancreas-kidney transplantation; DWFG; PTx; type 2 diabetes mellitus; death with a functioning graft; International Pancreas Transplant Registry; BMI

Background In the past, type 2 (C-peptide positive) diabetes mellitus (DM) was a contraindication for simultaneous pancreas-kidney transplantation (SPKT). Study Design We retrospectively analyzed outcomes in SPKT recipients according to pretransplantation C-peptide levels ≥2.0 ng/mL or < 2.0 ng/m...