Making sense out of missense mutations: Mechanistic dissection of Notch receptors through structure‐function studies in Drosophila - Yamamoto, Shinya (Development, growth & differentiation, 2020)
Keywords: Alleles; Amino Acid Substitution; Animals; cancer; Drosophila; Drosophila melanogaster; Drosophila Proteins - chemistry; Drosophila Proteins - genetics; Drosophila Proteins - metabolism; Gene mapping; Genes; Genetic screening; Homeostasis; Insects; Kinases; Mendelian diseases; Missense mutation; Mutants; Mutation; Mutation, Missense; Notch signaling pathway; Notch1 protein; Phenotypes; Protein Domains; Receptor mechanisms; Receptors, Notch - chemistry; Receptors, Notch - genetics; Receptors, Notch - metabolism; Signal transduction; structure function analysis; Structure-Activity Relationship; Structure-function relationships; variants of unknown significance (VUS); Notch signaling pathway; Mendelian diseases; cancer; Drosophila melanogaster; structure function analysis; variants of unknown significance (VUS)