Maternal and fetal outcomes of pregnancy occurring after a diagnosis of immune-mediated thrombotic thrombocytopenic purpura

• Published in: Annals of hematology Vol. 101; no. 10; pp. 2159 - 2167
• Main Authors: Brown, Jenna, Potugari, Bindu, Mazepa, Marshall A., Kohli, Ruhail, Moliterno, Alison R., Brodsky, Robert A., Vaught, Jason A., Burwick, Richard, Chaturvedi, Shruti
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2022; Springer Nature B.V
• Subjects: ADAMTS13 Protein; Female; HELLP Syndrome - diagnosis; Hematology; Humans; Medical diagnosis; Medicine; Medicine & Public Health; Oncology; Original Article; Pre-Eclampsia - diagnosis; Pre-Eclampsia - epidemiology; Preeclampsia; Pregnancy; Purpura; Purpura, Thrombocytopenic, Idiopathic; Purpura, Thrombotic Thrombocytopenic - diagnosis; Purpura, Thrombotic Thrombocytopenic - therapy; Recurrence; Retrospective Studies; Pregnancy; Thrombotic thrombocytopenic purpura; ADAMTS13; Preeclampsia

Pregnancy is a well-established trigger for a first episode or relapse of immune thrombotic thrombocytopenic purpura (iTTP). Other outcomes of subsequent pregnancy after a diagnosis of iTTP are less well described. We conducted this retrospective cohort study to evaluate maternal and fetal outcomes...