Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics - Liang, Jinliang; Liu, Huanyi; Lv, Guo; Chen, Xiaotong; Yang, Zhaoshou; Hu, Kunhua; Sun, Hongyan (Lipids in health and disease, 2025)
Keywords: Alanine Transaminase - blood; Animals; Aspartate Aminotransferases - blood; Cholesterol - metabolism; Diet, High-Fat - adverse effects; Drug therapy; Fatty liver; Fatty Liver - drug therapy; Fatty Liver - metabolism; Fatty Liver - pathology; Lipid Metabolism - drug effects; Lipidomics; Liver - drug effects; Liver - metabolism; Liver - pathology; Male; Medical research; Medicine, Experimental; Metabolic dysfunction-associated fatty liver disease; Metabolomics; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease - drug therapy; Non-alcoholic Fatty Liver Disease - metabolism; Non-alcoholic Fatty Liver Disease - pathology; Pharmacokinetics; Physiological aspects; Proteomics; Tirzepatide; Triglycerides - metabolism; China; Metabolomics; Lipidomics; Tirzepatide; Metabolic dysfunction-associated fatty liver disease; Proteomics