Maturity onset diabetes of the young due to HNF1A variants in Croatia

• Published in: Biochemia Medica Vol. 28; no. 2; p. 020703
• Main Authors: Pavić, Tamara, Juszczak, Agata, Pape Medvidović, Edita, Burrows, Carla, Šekerija, Mario, Bennett, Amanda J, Ćuća Knežević, Jadranka, Gloyn, Anna L, Lauc, Gordan, McCarthy, Mark I, Gornik, Olga, Owen, Katharine R
• Format: Journal Article Paper
• Language: English
• Published: Croatia Medicinska naklada 15.06.2018; Croatian Society of Medical Biochemistry and Laboratory Medicine
• Subjects: Adolescent; Adult; Aged; Alleles; Autoantibodies - blood; Biomarkers - blood; C-Peptide - blood; Croatia - epidemiology; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - genetics; Female; Gene Expression; Gene Frequency; Genetic Testing; Hepatocyte Nuclear Factor 1-alpha - genetics; Hepatocyte Nuclear Factor 1-alpha - immunology; HNF1A; Humans; Insulin-Secreting Cells - immunology; Insulin-Secreting Cells - pathology; Male; maturity onset diabetes of the young (MODY); Middle Aged; monogenic diabetes; Mutation; Original Papers; Prevalence; prevalence study; Registries; Sequence Analysis, DNA; prevalence study; HNF1A; maturity onset diabetes of the young (MODY); monogenic diabetes

Maturity onset diabetes of the young due to mutations (HNF1A-MODY) is the most frequent form of monogenic diabetes in adults. It is often misdiagnosed as type 1 or type 2 diabetes, but establishing genetic diagnosis is important, as treatment differs from the common types of diabetes. HNF1A-MODY has...