Detection of Borna disease virus p24 RNA in peripheral blood cells from Brazilian mood and psychotic disorder patients

• Published in: Journal of affective disorders Vol. 90; no. 1; pp. 43 - 47
• Main Authors: Miranda, Helen Cristina, Odebrecht Vargas Nunes, Sandra, Sanches Calvo, Eberson, Suzart, Sérgio, Nakagawa Itano, Eiko, Watanabe, Maria Angelica Ehara
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 2006; Elsevier
• Subjects: Adolescent; Adult; Adult and adolescent clinical studies; BDV; Biological and medical sciences; Borna Disease - epidemiology; Borna Disease - genetics; Borna Disease - virology; Borna disease virus - genetics; Borna disease virus - isolation & purification; Brazil - epidemiology; Depression; Diagnostic and Statistical Manual of Mental Disorders; DNA Primers - genetics; Female; Humans; Leukocytes, Mononuclear - virology; Male; Medical sciences; Middle Aged; Mood and psychotic disorders; Mood disorders; Mood Disorders - epidemiology; Mood Disorders - genetics; Mood Disorders - virology; p24 RNA; Prevalence; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral - genetics; Schizophrenia; Schizophrenia - epidemiology; Schizophrenia - genetics; Schizophrenia - virology; Sensitivity and Specificity; Sequence Analysis, DNA; Viral Proteins - genetics; Brazil; BDV; Mood and psychotic disorders; p24 RNA; Bornavirus; Human; Mood disorder; Schizoaffective psychosis; Prevalence; RNA; Depression; Male; Epidemiology; Bornaviridae; Infection; Virus; Psychosis; Mononegavirales; Blood cell; Viral disease; Female; Borna disease; Reverse transcription polymerase chain reaction
• ISSN: 0165-0327; 1573-2517
• DOI: 10.1016/j.jad.2005.10.008

Borna disease virus (BDV) is a virus that naturally infects a broad range of warm-blooded animals. BDV is an enveloped virus, non-segmented, negative-stranded RNA genome and has an organization characteristic of a member of Bornaviridae in the order of Mononegavirale. In the present work we investig...