Neurohormonal Activation in Acute Heart Failure: Results from VERITAS

• Published in: Cardiology Vol. 119; no. 2; pp. 96 - 105
• Main Authors: Milo-Cotter, Olga, Cotter-Davison, Beth, Lombardi, Carlo, Sun, Hengrui, Bettari, Luca, Bugatti, Silvia, Rund, Michele, Metra, Marco, Kaluski, Edo, Kobrin, Isaac, Frey, Aline, Rainisio, Maurizio, McMurray, John J.V., Teerlink, John R., Cotter-Davison, Gad
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.01.2011
• Subjects: Age; Aged; Aged, 80 and over; Biomarkers; Biomarkers - blood; Blood pressure; C-reactive protein; C-Reactive Protein - analysis; Creatinine; Cytokines; Endothelin 1; Endothelin receptors; Female; Heart diseases; Heart failure; Heart Failure - blood; Heart Failure - etiology; Humans; Immunoassay; Inflammation; Interleukin 6; Interleukin-6 - blood; Male; Medical prognosis; Middle Aged; Mortality; Natriuretic Peptide, Brain - blood; Neurotransmitter Agents - blood; Norepinephrine; Norepinephrine - blood; Original Research; Pathogenesis; plasminogen; Plasminogen Activator Inhibitor 1 - blood; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Sodium; t-Plasminogen activator; Tissue Plasminogen Activator - blood; Troponin I; Troponin I - blood; Von Willebrand factor; von Willebrand Factor - analysis; Heart failure; Inflammation; Prognosis

Objectives: Recent heart failure studies have suggested that inflammatory and immune system activation are associated with increased levels of cytokines, chemokines and inflammatory proteins during acutely decompensated heart failure. The objectives of this substudy were to evaluate the role of neur...