Effect of diet on plasma total antioxidant status in phenylketonuric patients
Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many antioxidants. The aim of this study was to evaluate the effect of diet on plasma total antioxidant status in our PKU patients. Twenty-two PKU pat...
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Published in | European Journal of Clinical Nutrition Vol. 57; no. 2; pp. 383 - 387 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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Basingstoke
Nature Publishing
01.02.2003
Nature Publishing Group |
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Abstract | Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many antioxidants.
The aim of this study was to evaluate the effect of diet on plasma total antioxidant status in our PKU patients.
Twenty-two PKU patients on strict diet (group A), 24 PKU patients who did not accurately follow their dietary control (group B) and 40 healthy children (controls) of comparable age took part in this study. Nutrients, as well as blood levels of lipids, vitamin C, beta-carotene and alpha-tocopherol were evaluated in all groups. Vitamin C intake and its blood levels did not differ between the groups. However, the intake of beta-carotene, alpha-tocopherol (2211+/-116, 14+/-1.0 mg/24 h) and their blood levels (0.7+/-0.09, 34+/-0.9 micro mol/l) in group A were statistically significantly higher (P<0.001) as compared with those of group B (1352+/-118, 10+/-1.0 mg/24 h and 0.49+/-0.08, 22+/-0.6 micromol/l) and controls (1290+/-120, 9.0+/-0.9 mg/24 h and 0.40+/-0.09, 24+/-1.6 micromol/l). Lipid intakes and their blood levels were lower in patients on the strict diet. Plasma total antioxidant status was higher in the same group of patients (group A). Additionally, positive correlations were found between the antioxidant vitamin blood levels and the plasma total antioxidant status in the groups, especially in the group A. PKU patients of group A showed significantly higher antioxidant status (1.6+/-0.2 mmol/l) as compared with those of group B (1.0+/-0.19 mmol/l; P<0.001) and controls (1.01+/-0.2 mmol/l).
The high plasma antioxidant status in patients with PKU, especially in those with a good compliance with their diet, is possibly due to the amounts of antioxidants which are present in their special low Phe vegetarian diet. |
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AbstractList | BACKGROUNDPhenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many antioxidants.AIMThe aim of this study was to evaluate the effect of diet on plasma total antioxidant status in our PKU patients.METHODS, RESULTSTwenty-two PKU patients on strict diet (group A), 24 PKU patients who did not accurately follow their dietary control (group B) and 40 healthy children (controls) of comparable age took part in this study. Nutrients, as well as blood levels of lipids, vitamin C, beta-carotene and alpha-tocopherol were evaluated in all groups. Vitamin C intake and its blood levels did not differ between the groups. However, the intake of beta-carotene, alpha-tocopherol (2211+/-116, 14+/-1.0 mg/24 h) and their blood levels (0.7+/-0.09, 34+/-0.9 micro mol/l) in group A were statistically significantly higher (P<0.001) as compared with those of group B (1352+/-118, 10+/-1.0 mg/24 h and 0.49+/-0.08, 22+/-0.6 micromol/l) and controls (1290+/-120, 9.0+/-0.9 mg/24 h and 0.40+/-0.09, 24+/-1.6 micromol/l). Lipid intakes and their blood levels were lower in patients on the strict diet. Plasma total antioxidant status was higher in the same group of patients (group A). Additionally, positive correlations were found between the antioxidant vitamin blood levels and the plasma total antioxidant status in the groups, especially in the group A. PKU patients of group A showed significantly higher antioxidant status (1.6+/-0.2 mmol/l) as compared with those of group B (1.0+/-0.19 mmol/l; P<0.001) and controls (1.01+/-0.2 mmol/l).CONCLUSIONSThe high plasma antioxidant status in patients with PKU, especially in those with a good compliance with their diet, is possibly due to the amounts of antioxidants which are present in their special low Phe vegetarian diet. Background: Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many antioxidants.Aim: The aim of this study was to evaluate the effect of diet on plasma total antioxidant status in our PKU patients.Methods, Results: Twenty-two PKU patients on strict diet (group A), 24 PKU patients who did not accurately follow their dietary control (group B) and 40 healthy children (controls) of comparable age took part in this study. Nutrients, as well as blood levels of lipids, vitamin C, β-carotene and α-tocopherol were evaluated in all groups. Vitamin C intake and its blood levels did not differ between the groups. However, the intake of β-carotene, α-tocopherol (2211±116, 14±1.0 mg/24 h) and their blood levels (0.7±0.09, 34±0.9 µmol/l) in group A were statistically significantly higher (P<0.001) as compared with those of group B (1352±118, 10±1.0 mg/24 h and 0.49±0.08, 22±0.6 µmol/l) and controls (1290±120, 9.0±0.9 mg/24 h and 0.40±0.09, 24±1.6 µmol/l). Lipid intakes and their blood levels were lower in patients on the strict diet. Plasma total antioxidant status was higher in the same group of patients (group A). Additionally, positive correlations were found between the antioxidant vitamin blood levels and the plasma total antioxidant status in the groups, especially in the group A. PKU patients of group A showed significantly higher antioxidant status (1.6±0.2 mmol/l) as compared with those of group B (1.0±0.19 mmol/l; P<0.001) and controls (1.01±0.2 mmol/l).Conclusions: The high plasma antioxidant status in patients with PKU, especially in those with a good compliance with their diet, is possibly due to the amounts of antioxidants which are present in their special low Phe vegetarian diet. Background: Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many antioxidants. Aim: The aim of this study was to evaluate the effect of diet on plasma total antioxidant status in our PKU patients. Methods, Results: Twenty-two PKU patients on strict diet (group A), 24 PKU patients who did not accurately follow their dietary control (group B) and 40 healthy children (controls) of comparable age took part in this study. Nutrients, as well as blood levels of lipids, vitamin C, beta-carotene and alpha-tocopherol were evaluated in all groups. Vitamin C intake and its blood levels did not differ between the groups. However, the intake of beta-carotene, alpha-tocopherol (2211 +/- 116, 14 +/- 1.0 mg/24 h) and their blood levels (0.7 +/- 0.09, 34 +/- 0.9 micromol/l) in group A were statistically significantly higher (P less than 0.001) as compared with those of group B (1352 +/- 118, 10 +/- 1.0 mg/24 h and 0.49 +/- 0.08, 22 +/- 0.6 micromol/l) and controls (1290 +/- 120, 9.0 +/- 0.9 mg/24 h and 0.40 +/- 0.09, 24 +/- 1.6 micromol/l). Lipid intakes and their blood levels were lower in patients on the strict diet. Plasma total antioxidant status was higher in the same group of patients (group A). Additionally, positive correlations were found between the antioxidant vitamin blood levels and the plasma total antioxidant status in the groups, especially in the group A. PKU patients of group A showed significantly higher antioxidant status (1.6 +/- 0.2 mmol/l) as compared with those of group B (1.0 +/- 0.19 mmol/l; P<0.001) and controls (1.01 +/- 0.2 mmol/l). Conclusions: The high plasma antioxidant status in patients with PKU, especially in those with a good compliance with their diet, is possibly due to the amounts of antioxidants which are present in their special low Phe vegetarian diet. [PUBLICATION ABSTRACT] Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many antioxidants. The aim of this study was to evaluate the effect of diet on plasma total antioxidant status in our PKU patients. Twenty-two PKU patients on strict diet (group A), 24 PKU patients who did not accurately follow their dietary control (group B) and 40 healthy children (controls) of comparable age took part in this study. Nutrients, as well as blood levels of lipids, vitamin C, beta-carotene and alpha-tocopherol were evaluated in all groups. Vitamin C intake and its blood levels did not differ between the groups. However, the intake of beta-carotene, alpha-tocopherol (2211+/-116, 14+/-1.0 mg/24 h) and their blood levels (0.7+/-0.09, 34+/-0.9 micro mol/l) in group A were statistically significantly higher (P<0.001) as compared with those of group B (1352+/-118, 10+/-1.0 mg/24 h and 0.49+/-0.08, 22+/-0.6 micromol/l) and controls (1290+/-120, 9.0+/-0.9 mg/24 h and 0.40+/-0.09, 24+/-1.6 micromol/l). Lipid intakes and their blood levels were lower in patients on the strict diet. Plasma total antioxidant status was higher in the same group of patients (group A). Additionally, positive correlations were found between the antioxidant vitamin blood levels and the plasma total antioxidant status in the groups, especially in the group A. PKU patients of group A showed significantly higher antioxidant status (1.6+/-0.2 mmol/l) as compared with those of group B (1.0+/-0.19 mmol/l; P<0.001) and controls (1.01+/-0.2 mmol/l). The high plasma antioxidant status in patients with PKU, especially in those with a good compliance with their diet, is possibly due to the amounts of antioxidants which are present in their special low Phe vegetarian diet. |
Audience | Professional Academic |
Author | TSAKIRIS, S KARIKAS, G. A SCHULPIS, K. H MOUKAS, M BEHRAKIS, P |
Author_xml | – sequence: 1 givenname: K. H surname: SCHULPIS fullname: SCHULPIS, K. H organization: Institute of Child Health, Aghia Sophia Children's Hospital, Athens, Greece – sequence: 2 givenname: S surname: TSAKIRIS fullname: TSAKIRIS, S organization: Department of Experimental Physiology, University of Athens, Medical School, Athens, Greece – sequence: 3 givenname: G. A surname: KARIKAS fullname: KARIKAS, G. A organization: Pharmacokinetics and Parenteral Nutrition Unit, Aghia Sophia Children's Hospital, Athens, Greece – sequence: 4 givenname: M surname: MOUKAS fullname: MOUKAS, M organization: Department of Experimental Physiology, University of Athens, Medical School, Athens, Greece – sequence: 5 givenname: P surname: BEHRAKIS fullname: BEHRAKIS, P organization: Department of Experimental Physiology, University of Athens, Medical School, Athens, Greece |
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Cites_doi | 10.1177/000992288902801007 10.1093/oxfordjournals.aje.a116964 10.1093/ajcn/58.3.334 10.1161/01.CIR.94.11.2720 10.1016/0009-8981(90)90218-H 10.1093/ajcn/68.4.778 10.1146/annurev.nu.16.070196.000411 10.1016/0014-5793(94)80391-9 10.1093/ajcn/62.3.591 10.3109/10715769709097822 10.1097/00043798-199406000-00002 10.1093/ajcn/69.2.261 10.1016/0003-9861(90)90508-V 10.1056/NEJM199605023341803 10.1042/cs0840407 10.1177/000456328602300505 10.1161/01.RES.73.3.534 10.1016/0005-2760(91)90164-D 10.1093/ajcn/72.4.976 10.1093/ajcn/48.3.712 10.1007/BF03343978 |
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Keywords | Human Nervous system diseases Phenylketonuria vitamin C Vegetarian diet Metabolic diseases β-carotene Antioxidant Enzymopathy antioxidant status Genetic disease Blood plasma Diet Child Aminoacid disorder α-tocopherol |
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References | Frolich, L, Riederer, P 1995; 45 Pan Wan Ham, Chia Jung Chin, Chin Tou Shew 1993; 58 Wendel, U, Koppelkamm, M, Hummel, W, Sauder, J 1990; 192 Halliwell, B, Gutteridge, JMC 1989 Paul, AA, Southgate, DA, Russel, J 1980 Weststrate, JA, Van het Hof, KH 1995; 62 Van Bakel, MM, Printezen, G, Wermuth, B, Weismann, UM 2000; 12 Hess, D, Keller, HE, Oberlin, B, Bonfanti, R, Schuep, W 1991; 61 Jushi, L, Folsom, A, Prineas, R, Mink, P, Bostick, R 1996; 334 Schulpis, KH, Scarpalezou, A 1988; 28 Sun, JZ, Kaur, H, Hadliwell, B, Li, Xz 1993; 73 Vahouny, GV 1982; 41 Sato, K, Niki, E, Shimasaki, H 1990; 279 Hurnham, DL, Davies, JA, Crump, BJ 1986; 23 Pietinen, R, Rimm, E, Korhonen, P, Hartman, A, Willet, W 1996; 94 Parks, EJ, German, JB, Davis, PA 1998; 63 Knekt, P, Reunanen, A, Sappanen, R 1994; 139 Miller, NJ, Rice-Evans, C, Davies, MJ, Copinathan, V, Milner, A 1993; 84 Klipstein-Grobusch, K, Geleijnse, J, Den Breeijen, J, Boeing, H, Hofman, A, Grober, D, Witteman, J 1999; 69 Reaven, PD, Witzturn, JL 1996; 16 Vuilleumier, JP, Keek, E 1991; 5 Scriver, C, Kaufman, S, Eisensmith, R, Woo, S 2000 Jialal, J, Norkus, EP, Cristol, J 1991; 1086 Dwyer, TT 1988; 48 Faggiano, A, Pivonello, R, Melis, D, Alfieri, R, Filippela, M, Spagnuolo, G, Salvatore, F, Lombardi, G, Colao, A 2002; 25 Sacks, F 1994; 1 Strube, M, Haenen, GR, Van den Berg, H, Bast, A 1997; 26 Van der Vliet, A, O'Neil, CA, Halliwell, B, Cross, CE, Kaur, H 1994; 339 K Sato (BF1601529_CR18) 1990; 279 J Jialal (BF1601529_CR7) 1991; 1086 PD Reaven (BF1601529_CR16) 1996; 16 M Strube (BF1601529_CR21) 1997; 26 TT Dwyer (BF1601529_CR1) 1988; 48 L Jushi (BF1601529_CR8) 1996; 334 EJ Parks (BF1601529_CR13) 1998; 63 P Knekt (BF1601529_CR10) 1994; 139 B Halliwell (BF1601529_CR4) 1989 C Scriver (BF1601529_CR20) 2000 KH Schulpis (BF1601529_CR19) 1988; 28 A Faggiano (BF1601529_CR2) 2002; 25 K Klipstein-Grobusch (BF1601529_CR9) 1999; 69 D Hess (BF1601529_CR5) 1991; 61 Pan Wan Ham (BF1601529_CR12) 1993; 58 JP Vuilleumier (BF1601529_CR26) 1991; 5 AA Paul (BF1601529_CR14) 1980 MM Van Bakel (BF1601529_CR24) 2000; 12 R Pietinen (BF1601529_CR15) 1996; 94 DL Hurnham (BF1601529_CR6) 1986; 23 F Sacks (BF1601529_CR17) 1994; 1 GV Vahouny (BF1601529_CR23) 1982; 41 NJ Miller (BF1601529_CR11) 1993; 84 U Wendel (BF1601529_CR27) 1990; 192 L Frolich (BF1601529_CR3) 1995; 45 A Van der Vliet (BF1601529_CR25) 1994; 339 JZ Sun (BF1601529_CR22) 1993; 73 JA Weststrate (BF1601529_CR28) 1995; 62 |
References_xml | – volume: 73 start-page: 534 year: 1993 end-page: 549 article-title: Use of aromatic phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo publication-title: Circul. Res. contributor: fullname: Li, Xz – volume: 139 start-page: 1180 year: 1994 end-page: 1189 article-title: Antioxidant vitamin intake and coronary mortality in a longitudinal population study publication-title: Am. J. Epidemiol. contributor: fullname: Sappanen, R – volume: 12 start-page: 976 year: 2000 end-page: 981 article-title: Antioxidant and thyroid hormone status in selenium deficient phenylketonuric and hyperphenylalaninemic patients publication-title: Am. J. Clin. Nutr. contributor: fullname: Weismann, UM – start-page: 110 year: 1989 end-page: 119 publication-title: Free radicals in Biology and Medicine contributor: fullname: Gutteridge, JMC – volume: 23 start-page: 514 year: 1986 end-page: 520 article-title: The use of different lipids to express vitamin E status publication-title: Ann. Clin. Biochem. contributor: fullname: Crump, BJ – year: 1980 publication-title: The Composition of the Food contributor: fullname: Russel, J – volume: 26 start-page: 515 year: 1997 end-page: 521 article-title: Pitfalls in a method for assessment of total antioxidant capacity publication-title: Free Radic. Res. contributor: fullname: Bast, A – volume: 62 start-page: 591 year: 1995 end-page: 597 article-title: Sucrose polyester and plasma carotenoid concentration in healthy subjects publication-title: Am. J. Clin. Nutr. contributor: fullname: Van het Hof, KH – volume: 192 start-page: 165 year: 1990 end-page: 170 article-title: A new approach to the newborn screening for hyperphenylalaninemias use -phenylalanine dehydrogenase and microtiter plates publication-title: Clin. Chim. Acta contributor: fullname: Sauder, J – volume: 5 start-page: 25 year: 1991 end-page: 34 article-title: Fluorometric assay of vitamin C publication-title: J. Micronutr. Anal. contributor: fullname: Keek, E – volume: 69 start-page: 261 year: 1999 end-page: 266 article-title: Dietary antioxidants and risk of myocardial infarction in the elderly: the Rotterdam Study publication-title: Am. J. Clin. Nutr. contributor: fullname: Witteman, J – volume: 94 start-page: 2720 year: 1996 end-page: 2727 article-title: Intake of Dietary fiber and risk of coronary heart disease in a Cohort of Finnish Men publication-title: Circulation contributor: fullname: Willet, W – volume: 1086 start-page: 134 year: 1991 end-page: 138 article-title: β-Carotene inhibits the oxidative modification of LDL publication-title: Biochim. Biophys. Acta contributor: fullname: Cristol, J – volume: 334 start-page: 1156 year: 1996 end-page: 1162 article-title: Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women publication-title: New Engl. J. Med. contributor: fullname: Bostick, R – volume: 41 start-page: 2801 year: 1982 end-page: 2806 article-title: Dietary fiber, lipid metabolism and atherosclerosis publication-title: Fed. Proc contributor: fullname: Vahouny, GV – volume: 84 start-page: 407 year: 1993 end-page: 412 article-title: A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates publication-title: Clin. Soc. (Colch.) contributor: fullname: Milner, A – volume: 25 start-page: 142 year: 2002 end-page: 151 article-title: Evaluation of circulating levels and renal clearence of natural amino acids in patients with Cushing disease publication-title: J. Endocrinol. Invest. contributor: fullname: Colao, A – volume: 58 start-page: 334 year: 1993 end-page: 359 article-title: Haemostatic factors and blood lipids in Buddishist vegetarian and omnivores publication-title: Am. J. Clin. Nutr. contributor: fullname: Chin Tou Shew – volume: 339 start-page: 89 year: 1994 end-page: 92 article-title: Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite publication-title: FEBS Lett. contributor: fullname: Kaur, H – volume: 28 start-page: 466 year: 1988 end-page: 469 article-title: Triglycerides, cholesterol. HDL, LDL and VLDL cholesterol in serum pf phenylketonuric patients publication-title: Clin. Pediatr. contributor: fullname: Scarpalezou, A – volume: 16 start-page: 51 year: 1996 end-page: 71 article-title: Oxidised low density lipoproteins in atherogenesis publication-title: A. Rev. Nut. contributor: fullname: Witzturn, JL – volume: 279 start-page: 402 year: 1990 end-page: 405 article-title: Free radical mediated chain oxidation of LDL and its synergistic inhibition by vitamin E and vitamin C publication-title: Arch. Biochem. Biophy. contributor: fullname: Shimasaki, H – volume: 48 start-page: 712 year: 1988 end-page: 738 article-title: Health aspects of vegetarian diet publication-title: Am. J. Clin. Nutr. contributor: fullname: Dwyer, TT – volume: 1 start-page: 3 year: 1994 end-page: 8 article-title: Dietary fats and coronary heart disease publication-title: J. Cardiovasc. Risk contributor: fullname: Sacks, F – volume: 45 start-page: 443 year: 1995 end-page: 446 article-title: Free radical mechanisms of Alzheimer Type and the potential for antioxidative treatment publication-title: Arzeim. Forsch. Drug Res. contributor: fullname: Riederer, P – start-page: 1667 year: 2000 end-page: 1724 article-title: The Hyperphenylalaninemias publication-title: The Metabolic and Molecular Bases of Inherited Disease contributor: fullname: Woo, S – volume: 61 start-page: 232 year: 1991 end-page: 238 article-title: Simultaneous determination of retinol, tocopherols, carotenes and lycopene in plasma by means of HPLC on reversed phase publication-title: Int. J. Vitam. Nutr. Res. contributor: fullname: Schuep, W – volume: 63 start-page: 778 year: 1998 end-page: 785 article-title: Reduced oxidative susceptibility of LDL from patients participating in an intensive atherosclerosis treatment program publication-title: Am. J. Clin. Nutr. contributor: fullname: Davis, PA – volume: 28 start-page: 466 year: 1988 ident: BF1601529_CR19 publication-title: Clin. Pediatr. doi: 10.1177/000992288902801007 contributor: fullname: KH Schulpis – volume: 139 start-page: 1180 year: 1994 ident: BF1601529_CR10 publication-title: Am. J. Epidemiol. doi: 10.1093/oxfordjournals.aje.a116964 contributor: fullname: P Knekt – volume: 58 start-page: 334 year: 1993 ident: BF1601529_CR12 publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/58.3.334 contributor: fullname: Pan Wan Ham – volume: 94 start-page: 2720 year: 1996 ident: BF1601529_CR15 publication-title: Circulation doi: 10.1161/01.CIR.94.11.2720 contributor: fullname: R Pietinen – volume: 192 start-page: 165 year: 1990 ident: BF1601529_CR27 publication-title: Clin. Chim. Acta doi: 10.1016/0009-8981(90)90218-H contributor: fullname: U Wendel – volume: 63 start-page: 778 year: 1998 ident: BF1601529_CR13 publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/68.4.778 contributor: fullname: EJ Parks – volume: 16 start-page: 51 year: 1996 ident: BF1601529_CR16 publication-title: A. Rev. Nut. doi: 10.1146/annurev.nu.16.070196.000411 contributor: fullname: PD Reaven – volume: 45 start-page: 443 year: 1995 ident: BF1601529_CR3 publication-title: Arzeim. Forsch. Drug Res. contributor: fullname: L Frolich – volume: 339 start-page: 89 year: 1994 ident: BF1601529_CR25 publication-title: FEBS Lett. doi: 10.1016/0014-5793(94)80391-9 contributor: fullname: A Van der Vliet – volume: 62 start-page: 591 year: 1995 ident: BF1601529_CR28 publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/62.3.591 contributor: fullname: JA Weststrate – volume: 26 start-page: 515 year: 1997 ident: BF1601529_CR21 publication-title: Free Radic. Res. doi: 10.3109/10715769709097822 contributor: fullname: M Strube – volume: 41 start-page: 2801 year: 1982 ident: BF1601529_CR23 publication-title: Fed. Proc contributor: fullname: GV Vahouny – start-page: 1667 volume-title: The Metabolic and Molecular Bases of Inherited Disease year: 2000 ident: BF1601529_CR20 contributor: fullname: C Scriver – start-page: 110 volume-title: Free radicals in Biology and Medicine year: 1989 ident: BF1601529_CR4 contributor: fullname: B Halliwell – volume: 1 start-page: 3 year: 1994 ident: BF1601529_CR17 publication-title: J. Cardiovasc. Risk doi: 10.1097/00043798-199406000-00002 contributor: fullname: F Sacks – volume: 69 start-page: 261 year: 1999 ident: BF1601529_CR9 publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/69.2.261 contributor: fullname: K Klipstein-Grobusch – volume: 279 start-page: 402 year: 1990 ident: BF1601529_CR18 publication-title: Arch. Biochem. Biophy. doi: 10.1016/0003-9861(90)90508-V contributor: fullname: K Sato – volume: 334 start-page: 1156 year: 1996 ident: BF1601529_CR8 publication-title: New Engl. J. Med. doi: 10.1056/NEJM199605023341803 contributor: fullname: L Jushi – volume: 84 start-page: 407 year: 1993 ident: BF1601529_CR11 publication-title: Clin. Soc. (Colch.) doi: 10.1042/cs0840407 contributor: fullname: NJ Miller – volume: 23 start-page: 514 year: 1986 ident: BF1601529_CR6 publication-title: Ann. Clin. Biochem. doi: 10.1177/000456328602300505 contributor: fullname: DL Hurnham – volume: 73 start-page: 534 year: 1993 ident: BF1601529_CR22 publication-title: Circul. Res. doi: 10.1161/01.RES.73.3.534 contributor: fullname: JZ Sun – volume: 1086 start-page: 134 year: 1991 ident: BF1601529_CR7 publication-title: Biochim. Biophys. Acta doi: 10.1016/0005-2760(91)90164-D contributor: fullname: J Jialal – volume-title: The Composition of the Food year: 1980 ident: BF1601529_CR14 contributor: fullname: AA Paul – volume: 12 start-page: 976 year: 2000 ident: BF1601529_CR24 publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/72.4.976 contributor: fullname: MM Van Bakel – volume: 48 start-page: 712 year: 1988 ident: BF1601529_CR1 publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/48.3.712 contributor: fullname: TT Dwyer – volume: 61 start-page: 232 year: 1991 ident: BF1601529_CR5 publication-title: Int. J. Vitam. Nutr. Res. contributor: fullname: D Hess – volume: 5 start-page: 25 year: 1991 ident: BF1601529_CR26 publication-title: J. Micronutr. Anal. contributor: fullname: JP Vuilleumier – volume: 25 start-page: 142 year: 2002 ident: BF1601529_CR2 publication-title: J. Endocrinol. Invest. doi: 10.1007/BF03343978 contributor: fullname: A Faggiano |
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Snippet | Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains many... Background: Phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and... BACKGROUNDPhenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, is treated with a low Phe lifelong diet, which is a vegetarian and contains... |
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SubjectTerms | Analysis of Variance Antioxidants Antioxidants - metabolism Ascorbic acid Biological and medical sciences Blood Blood levels Carotene Child Diet Diet therapy Diet, Vegetarian - statistics & numerical data Female Health aspects Humans Lipids Male Medical disorders Medical sciences Metabolism Miscellaneous Nutrient deficiency Nutrients Patient outcomes Phenylalanine Phenylketonuria Phenylketonurias - blood Phenylketonurias - diet therapy Plasma Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Tocopherol Vegetarian diet Vegetarianism Vitamin A Vitamin C Vitamin E β-Carotene |
Title | Effect of diet on plasma total antioxidant status in phenylketonuric patients |
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