Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays - Li, Xilin; Le, Yuan; Seo, Ji-Eun; Guo, Xiaoqing; Li, Yuxi; Chen, Si; Mittelstaedt, Roberta A.; Moore, Nyosha; Guerrero, Sharon; Sims, Audrey; King, Sruthi T.; Atrakchi, Aisar H.; et al. (Regulatory toxicology and pharmacology, 2023)
Keywords: Animals; Chromosomal damage; Cricetinae; Cytochrome P450s; DNA Damage; Gene mutation; Hamster liver S9; Humans; Legal Medicine; Mammals; Mutagenesis; Mutagenicity Tests - methods; Mutagens - toxicity; Mutation; N-Nitroso propranolol; Nitrosamine impurities; Pharmacology & Pharmacy; Propranolol - toxicity; Rats; Toxicology; Cytochrome P450s; Hamster liver S9; Chromosomal damage; Nitrosamine impurities; Gene mutation; N-Nitroso propranolol