Increased prevalence of Parkinson's disease in soils with high arsenic levels

• Published in: Parkinsonism & related disorders Vol. 88; pp. 19 - 23
• Main Authors: Lee, Chien-Pang, Zhu, Chia-Hsin, Su, Che-Chun
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2021
• Subjects: Adult; Aged; Aged, 80 and over; Arsenic; Arsenic Poisoning - complications; Farms; Female; Geographic Mapping; Heavy metal; Humans; Male; Middle Aged; Parkinson Disease - epidemiology; Parkinson Disease - etiology; Parkinson Disease, Secondary - chemically induced; Parkinson Disease, Secondary - epidemiology; Parkinson's disease; Pesticides - adverse effects; Prevalence; Soil - chemistry; Spatial statistics; Taiwan - epidemiology; Taiwan; Parkinson's disease; Prevalence; Arsenic; Heavy metal; Spatial statistics

Exposure to arsenic (As)-containing pesticides was associated with an increased risk for Parkinson's disease (PD). Arsenic also induced in murine brains α-synuclein aggregates, a pathognomic feature of PD. People living on farms irrigated with high As water in Taiwan are likely exposed to incre...