Age-dependent effects of oxytocin in brain regions enriched with oxytocin receptors

• Published in: Psychoneuroendocrinology Vol. 160; p. 106666
• Main Authors: Xiao, Shanshan, Ebner, Natalie C, Manzouri, Amirhossein, Li, Tie-Qiang, Cortes, Diana S, Månsson, Kristoffer N T, Fischer, Håkan
• Format: Journal Article
• Language: English
• Published: England 01.02.2024
• Subjects: Administration, Intranasal; age; Brain - metabolism; Caudate Nucleus; Double-Blind Method; Humans; Magnetic Resonance Imaging; Medicin och hälsovetenskap; oxytocin; Oxytocin - metabolism; oxytocin receptor; Psychology; psykologi; quantitative data-driven analysis framework; Receptors, Oxytocin - metabolism; resting-state functional connectivity; Resting-state functional connectivity; Oxytocin; Oxytocin receptor; Age; Quantitative data-driven analysis framework

Although intranasal oxytocin administration to tap into central functions is the most commonly used non-invasive means for exploring oxytocin's role in human cognition and behavior, the way by which intranasal oxytocin acts on the brain is not yet fully understood. Recent research suggests that...