Hormone-free vs. follicle-stimulating hormone–primed infertility treatment of women with polycystic ovary syndrome using biphasic in vitro maturation: a randomized controlled trial

• Published in: Fertility and sterility Vol. 123; no. 2; pp. 253 - 261
• Main Authors: Vuong, Lan N., Ho, Vu N.A., Le, Anh H., Nguyen, Nam T., Pham, Toan D., Nguyen, Minh H.N., Le, Ho L., Le, Tien K., Ha, Anh N., Le, Xuyen T.H., Pham, Huy H., Tran, Cam T., Huynh, Bao G., Smitz, Johan E.J., Gilchrist, Robert B., Ho, Tuong M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2025
• Subjects: Adolescent; Adult; Embryo Transfer; Female; Fertility - drug effects; Fertility Agents, Female - administration & dosage; Fertility Agents, Female - adverse effects; Fertilization in Vitro - methods; Follicle Stimulating Hormone - administration & dosage; Humans; In Vitro Oocyte Maturation Techniques - methods; infertility; Infertility, Female - diagnosis; Infertility, Female - etiology; Infertility, Female - physiopathology; Infertility, Female - therapy; In vitro maturation; Live Birth; oocyte maturation; Oocyte Retrieval; Ovulation Induction - adverse effects; Ovulation Induction - methods; polycystic ovary syndrome; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - diagnosis; Polycystic Ovary Syndrome - physiopathology; Polycystic Ovary Syndrome - therapy; Pregnancy; Pregnancy Rate; Treatment Outcome; Young Adult; oocyte maturation; infertility; live birth; In vitro maturation; polycystic ovary syndrome

To compare oocyte maturation rates and pregnancy outcomes in women with polycystic ovary syndrome (PCOS) undergoing biphasic in vitro maturation (capacitation in vitro maturation [CAPA-IVM]) with vs. without follicle-stimulating hormone (FSH) priming. Randomized, controlled, assessor-blinded trial....