Early life stress unravels epistatic genetic associations of cortisol pathway genes with depression - Pereira, Sherliane Carla; Coeli-Lacchini, Fernanda Borchers; Pereira, Daniela Alves; Ferezin, Letícia Perticarrara; Menezes, Itiana Castro; Baes, Cristiane von Werne; Luizon, Marcelo Rizzatti; Juruena, Mario F.; Cleare, Anthony J.; Young, Allan H.; Lacchini, Riccardo (Journal of psychiatric research, 2024)
Keywords: Adult; Adverse Childhood Experiences; ATP Binding Cassette Transporter, Subfamily B - genetics; Cortisol; Depression; Depression - genetics; Early life stress; Epistasis; Epistasis, Genetic; Female; Genetic polymorphism; Genetic Predisposition to Disease; Humans; Hydrocortisone - metabolism; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Glucocorticoid - genetics; Receptors, Mineralocorticoid - genetics; Stress, Psychological - genetics; Suicidal Ideation; Suicide, Attempted; Young Adult; Depression; Early life stress; Cortisol; Epistasis; Genetic polymorphism