Characterization of the immune regulatory property of CD22+ CD9+ B cells

• Published in: Immunology Vol. 167; no. 3; pp. 328 - 339
• Main Authors: Yang, Gui, Suo, Limin, Hu, Suqin, Liu, Huazhen, Wang, Xinxin, Xiao, Xiaojun, Liu, Jie, Zeng, Xianhai, Hong, Jingyi, Guan, Li, Xue, Jinmei, Yang, Pingchang
• Format: Journal Article
• Language: English
• Published: Oxford Wiley Subscription Services, Inc 01.11.2022
• Subjects: airways; Allergic diseases; Allergic rhinitis; allergy; Antigens; B lymphocytes; CD19 antigen; CD22 antigen; CD4 antigen; CD9 antigen; Homeostasis; IL‐10; immune regulation; Immunoregulation; Immunotherapy; Lymphocytes; Lymphocytes B; Lymphocytes T; Rhinitis

Immunodisruptive homeostasis is recognized in allergic disorders. The mechanism of restoration of immunologic homeostasis in the body is not fully understood. Galectin‐9 (Gal9) and CD22 have immune regulatory functions. The goal of this study is to test the role of CD22+ CD9+ B regulatory cells in i...