Impact of Hormone Receptor Status and Ki-67 Expression on Disease-Free Survival in Patients Affected by High-risk Endometrial Cancer

• Published in: International journal of gynecological cancer Vol. 28; no. 3; pp. 505 - 513
• Main Authors: Di Donato, Violante, Iacobelli, Valentina, Schiavi, Michele Carlo, Colagiovanni, Vanessa, Pecorella, Irene, Palaia, Innocenza, Perniola, Giorgia, Marchetti, Claudia, Musella, Angela, Tomao, Federica, Monti, Marco, Muzii, Ludovico, Benedetti Panici, Pierluigi
• Format: Journal Article
• Language: English
• Published: England by the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology 01.03.2018; BMJ Publishing Group LTD
• Subjects: Aged; Endometrial cancer; Endometrial Neoplasms - metabolism; Endometrial Neoplasms - pathology; Estrogen Receptor alpha - biosynthesis; Female; Gynecology; Humans; Immunohistochemistry; Ki-67 Antigen - biosynthesis; Lymphatic Metastasis; Medical prognosis; Middle Aged; Neoplasm Recurrence, Local - metabolism; Neoplasm Recurrence, Local - pathology; Obstetrics; Receptors, Progesterone - biosynthesis; Risk Factors; Tumors

OBJECTIVESThe aim of this study was to evaluate the immunohistochemical (IHC) expression of Ki-67, estrogen receptors α (ERsα), and progesterone receptors (PRs) in high-risk endometrial cancer patients and to assess their prognostic impact. METHODS/MATERIALSImmunohistochemical expression of Ki-67, E...