Magnetic resonance imaging and spectroscopy for monitoring liver steatosis

• Published in: Journal of magnetic resonance imaging Vol. 28; no. 4; pp. 937 - 945
• Main Authors: Cowin, Gary J., Jonsson, Julie R., Bauer, Judith D., Ash, Susan, Ali, Azmat, Osland, Emma J., Purdie, David M., Clouston, Andrew D., Powell, Elizabeth E., Galloway, Graham J.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.10.2008
• Subjects: Adipose Tissue - pathology; Adult; Biopsy; Fatty Liver - etiology; Fatty Liver - metabolism; Fatty Liver - pathology; fatty liver disease; Female; Humans; Insulin Resistance; liver fat; Magnetic Resonance Imaging - methods; Magnetic Resonance Spectroscopy - methods; Male; Middle Aged; obesity; Obesity - complications; Obesity - metabolism; Obesity - pathology; Reproducibility of Results; Statistics, Nonparametric; Triglycerides - metabolism; weight loss

Purpose To compare noninvasive MRI and magnetic resonance spectroscopy (MRS) methods with liver biopsy to quantify liver fat content. Materials and Methods Quantification of liver fat was compared by liver biopsy, proton MRS, and MRI using in‐phase/out‐of‐phase (IP/OP) and plus/minus fat saturation...