Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma

• Published in: Cancer Vol. 122; no. 7; pp. 1017 - 1028
• Main Authors: Tricoli, James V., Blair, Donald G., Anders, Carey K., Bleyer, W. Archie, Boardman, Lisa A., Khan, Javed, Kummar, Shivaani, Hayes‐Lattin, Brandon, Hunger, Stephen P., Merchant, Melinda, Seibel, Nita L., Thurin, Magdalena, Willman, Cheryl L.
• Format: Journal Article
• Language: English
• Published: United States 01.04.2016
• Subjects: acute lymphoblastic leukemia (ALL); Adolescent; Adult; breast; Breast Neoplasms - pathology; colorectal; Colorectal Neoplasms - pathology; Female; Humans; Male; melanoma; Melanoma - pathology; Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology; sarcoma; Sarcoma - pathology; Young Adult; melanoma; sarcoma; colorectal; breast; acute lymphoblastic leukemia (ALL)

Adolescent and young adult (AYA) patients with cancer have not attained the same improvements in overall survival as either younger children or older adults. One possible reason for this disparity may be that the AYA cancers exhibit unique biologic characteristics, resulting in differences in clinic...