Excessive Daytime Sleepiness in Sleep Apnea: Any Role of Testosterone or Vitamin D?

• Published in: Physiological research Vol. 69; no. 5; pp. 907 - 917
• Main Authors: ŠIARNIK, P, JURÍK, M, HARDOŇOVÁ, M, KLOBUČNÍKOVÁ, K, VEVERKA, J, ŠURDA, P, TURČÁNI, P, KOLLÁR, B
• Format: Journal Article
• Language: English
• Published: Czech Republic Institute of Physiology 16.11.2020; Institute of Physiology of the Czech Academy of Sciences
• Subjects: Antihistamines; Apnea; Body Mass Index; Cardiovascular disease; Comorbidity; Daytime; Disorders of Excessive Somnolence - blood; Disorders of Excessive Somnolence - pathology; Fatigue; Histamine; Humans; Immunoassay; Laboratories; Male; Males; Middle Aged; Multiple regression analysis; Polysomnography - methods; Prospective Studies; Regression analysis; Restless legs syndrome; Sleep; Sleep and wakefulness; Sleep apnea; Sleep Apnea, Obstructive - blood; Sleep Apnea, Obstructive - pathology; Sleep deprivation; Sleep disorders; Testosterone; Testosterone - blood; United Kingdom - epidemiology; Variables; Vitamin D; Vitamin D - blood; Vitamin D Deficiency - blood; Vitamin D Deficiency - pathology; Vitamin deficiency; Vitamins - blood; United Kingdom

Recent studies reported association of sleep-disordered breathing (SDB) with testosterone and vitamin D deficiency. Low testosterone and vitamin D levels have been linked to fatigue and excessive daytime sleepiness (EDS). However, the impact of testosterone and vitamin D deficiency on EDS in subject...