The ecology and age structure of a highly pathogenic avian influenza virus outbreak in wild mute swans

• Published in: Parasitology Vol. 139; no. 14; pp. 1914 - 1923
• Main Authors: PYBUS, O. G., PERRINS, C. M., CHOUDHURY, B., MANVELL, R. J., NUNEZ, A., SCHULENBURG, B., SHELDON, B. C., BROWN, I. H.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.12.2012
• Subjects: Age Distribution; age structure; Animals; Animals, Wild - virology; Anseriformes - virology; antibodies; Antibodies, Viral - blood; Aquatic birds; avian influenza; Disease Outbreaks - veterinary; Ecology; Epidemiology; epizootic diseases; Hemagglutinins, Viral - genetics; immigration; Influenza A virus; Influenza A Virus, H5N1 Subtype - classification; Influenza A Virus, H5N1 Subtype - genetics; Influenza in Birds - epidemiology; Influenza in Birds - immunology; Influenza in Birds - mortality; Influenza in Birds - virology; Molecular Sequence Data; Mortality; nucleoproteins; Outbreaks; Phylogeny; polymerase chain reaction; swans; Time Factors; United Kingdom; United Kingdom - epidemiology; viruses; water birds; wild birds; United Kingdom; Avian influenza virus; phylogenetics; molecular clock; age structure; swans; serology

The first UK epizootic of highly pathogenic (HP) H5N1 influenza in wild birds occurred in 2008, in a population of mute swans that had been the subject of ornithological study for decades. Here we use an innovative combination of ornithological, phylogenetic and immunological approaches to investiga...