Lysophosphatidylcholine increases airway and capillary permeability in the isolated perfused rat lung

• Published in: Experimental lung research Vol. 11; no. 1; p. 1
• Main Authors: Lindahl, M, Hede, A R, Tagesson, C
• Format: Journal Article
• Language: English
• Published: England 1986
• Subjects: Animals; Blood Pressure - drug effects; Capillary Permeability - drug effects; In Vitro Techniques; Lung - metabolism; Lysophosphatidylcholines - pharmacology; Male; Perfusion; Pulmonary Circulation - drug effects; Rats; Rats, Inbred Strains

The effects of lysophosphatidylcholine (lysoPC) on airway and capillary permeability in the isolated perfused rat lung were investigated. We determined the influence of lysoPC on the passage of different-sized (326-722 dalton) polyethylene glycols (PEGs), both from the airways to the pulmonary circu...