Immunohistochemical Localization of Phosphodiesterase 10A in Multiple Mammalian Species

• Published in: The journal of histochemistry and cytochemistry Vol. 54; no. 11; pp. 1205 - 1213
• Main Authors: Coskran, Timothy M, Morton, Daniel, Menniti, Frank S, Adamowicz, Wendy O, Kleiman, Robin J, Ryan, Anne M, Strick, Christine A, Schmidt, Christopher J, Stephenson, Diane T
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA Histochemical Soc 01.11.2006; SAGE Publications
• Subjects: Animals; Brain - anatomy & histology; Brain - metabolism; Dogs; Humans; Immunohistochemistry; Macaca fascicularis; Mice; Organ Specificity; Phosphoric Diester Hydrolases - metabolism; Rats; Species Specificity; phosphodiesterase 10A; localization; striatum; phosphodiesterase; immunohistochemistry; testis; nuclear; enteric ganglia

A monoclonal antibody directed against the amino terminal of rat phosphodiesterase 10A (PDE10A) was used to localize PDE10A in multiple central nervous system (CNS) and peripheral tissues from mouse, rat, dog, cynomolgus macaque, and human. PDE10A immunoreactivity is strongly expressed in the CNS of...