Low-load resistance training to task failure with and without blood flow restriction: muscular functional and structural adaptations

• Published in: American journal of physiology. Regulatory, integrative and comparative physiology Vol. 318; no. 2; pp. R284 - R295
• Main Authors: Pignanelli, Christopher, Petrick, Heather L., Keyvani, Fatemeh, Heigenhauser, George J. F., Quadrilatero, Joe, Holloway, Graham P., Burr, Jamie F.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.02.2020
• Series: Physical Activity and Inactivity
• Subjects: Adaptation; Adaptation, Physiological; Adult; Blood flow; Fatigue tests; Flow resistance; Healthy Volunteers; Humans; Hypertrophy; Load resistance; Male; Mitochondria; Mitochondria, Muscle - metabolism; Muscle Contraction; Muscle Fatigue; Muscle Strength; Muscular function; Musculoskeletal system; Oxidation resistance; Performance indices; Physical Endurance; Physical training; Quadriceps Muscle - blood supply; Quadriceps Muscle - diagnostic imaging; Quadriceps Muscle - metabolism; Random Allocation; Rehabilitation; Repetition; Resistance Training; Skeletal muscle; Strength training; Structure-function relationships; Therapeutic Occlusion; Time Factors; Young Adult; high-resolution respirometry; repetition failure; BFR resistance exercise; capillary; mitochondria; low-load

The application of blood flow restriction (BFR) during resistance exercise is increasingly recognized for its ability to improve rehabilitation and for its effectiveness in increasing muscle hypertrophy and strength among healthy populations. However, direct comparison of the skeletal muscle adaptat...