Comparison of Different Types of Oral Adsorbent Therapy in Patients with Chronic Kidney Disease: A Multicenter, Randomized, Phase IV Clinical Trial

• Published in: Yonsei medical journal Vol. 62; no. 1; pp. 41 - 49
• Main Authors: Kee, Youn Kyung, Han, Sang Youb, Kang, Duk-Hee, Noh, Jung Woo, Jeong, Kyung Hwan, Kim, Gheun-Ho, Kim, Yang Wook, Kim, Beom Seok
• Format: Journal Article
• Language: English
• Published: Korea (South) Yonsei University College of Medicine 01.01.2021; 연세대학교의과대학
• Subjects: Adsorption; Carbon - administration & dosage; Carbon - therapeutic use; Creatinine - blood; Cross-Over Studies; Cystatin C - blood; Disease Progression; Female; Glomerular Filtration Rate - drug effects; Humans; Indican - blood; Male; Middle Aged; Original; Oxides - administration & dosage; Oxides - therapeutic use; Renal Insufficiency, Chronic - blood; Renal Insufficiency, Chronic - drug therapy; Renal Insufficiency, Chronic - physiopathology; Treatment Outcome; 의학일반; AST-120; Chronic kidney disease; DW-7202; adherence; preference

Oral adsorbents delay disease progression and improve uremic symptoms in patients with chronic kidney disease (CKD). DW-7202 is a newly developed oral adsorbent with high adsorptive selectivity for uremic toxins. We evaluated patient preference for and adherence to DW-7202 versus AST-120 therapy and...