Yeast extract inhibits the proliferation of renal cell carcinoma cells via regulation of iron metabolism

• Published in: Molecular medicine reports Vol. 20; no. 4; pp. 3933 - 3941
• Main Authors: Moon, Daeun, Kim, Jinu, Yoon, Sang‑Pil
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.10.2019; Spandidos Publications UK Ltd
• Subjects: Adjuvant treatment; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Antitumor activity; Apoptosis; Autophagy; Cancer; Carcinoma, Renal cell; Carcinoma, Renal Cell - metabolism; Carcinoma, Renal Cell - microbiology; Carcinoma, Renal Cell - therapy; Cell culture; Cell cycle; Cell Cycle Checkpoints - drug effects; Cell death; Cell Line; Cell Line, Tumor; Cell proliferation; Cell Proliferation - drug effects; Chemotherapy; Comparative analysis; Culture Media - chemistry; Culture Media - pharmacology; Cyclin D1; Fatty acids; Ferritin; Ferroptosis; Flow cytometry; Gastrointestinal Microbiome; Homeostasis; Humans; Ingredients; Instrument industry; Iron; Iron - metabolism; Kidney cancer; Kidney diseases; Kidney Neoplasms - metabolism; Kidney Neoplasms - microbiology; Kidney Neoplasms - therapy; Kinases; Metastasis; Microbiomes; Microbiota; Phagocytosis; Pharmaceutical industry; Renal cell carcinoma; Transferrins; Western blotting; Yeast; Yeasts - chemistry; Yeasts - physiology; United States; South Korea; Germany

The microbiome has recently attracted research interest in a variety of subjects, including cancer. In the present study, it was determined that reinforced clostridium media (RCM) for microbiome culture, exerts antitumor effects on renal cell carcinoma cells when compared to the microbiome 'X&#...