BAL Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications - Weathington, Nathaniel; O’Brien, Michael E.; Radder, Josiah; Whisenant, Thomas C.; Bleecker, Eugene R.; Busse, William W.; Erzurum, Serpil C.; Gaston, Benjamin; Hastie, Annette T.; Jarjour, Nizar N.; Meyers, Deborah A.; Milosevic, Jadranka; et al. (American journal of respiratory and critical care medicine, 2019)
Keywords: Adrenergic beta-Agonists - pharmacology; Adult; Asthma; Asthma - genetics; Asthma - metabolism; Biomarkers; Bronchoalveolar Lavage Fluid - cytology; Case-Control Studies; Cell cycle; Cells; Cyclic AMP - metabolism; Eosinophils - metabolism; Epithelial Cells - metabolism; Female; Gene expression; Gene Expression - drug effects; Gene Expression - genetics; Humans; In Vitro Techniques; Lymphocytes - metabolism; Macrophages, Alveolar - metabolism; Male; Neutrophils - metabolism; Original; Proteins; Sequence Analysis, RNA; Severity of Illness Index; Signal Transduction - genetics; THP-1 Cells - metabolism; asthma; genetics; β-agonist; bronchoalveolar lavage; gene expression