Catecholamines are present in a synaptic-like microvesicle-enriched fraction from bovine adrenal medulla

• Published in: Journal of neurochemistry Vol. 60; no. 5; p. 1746
• Main Authors: Annaert, W G, Llona, I, Backer, A C, Jacob, W A, De Potter, W P
• Format: Journal Article
• Language: English
• Published: England 01.05.1993
• Subjects: Adrenal Medulla - metabolism; Adrenal Medulla - ultrastructure; Animals; Autoradiography; Catecholamines - metabolism; Cattle; Centrifugation, Density Gradient; Cytochrome b Group - metabolism; Dopamine beta-Hydroxylase - metabolism; Microscopy, Immunoelectron; Subcellular Fractions - metabolism; Synaptic Vesicles - metabolism; Synaptic Vesicles - ultrastructure; Synaptophysin - metabolism

"Synaptic-like microvesicles" are present in all neuroendocrine cells and cell lines. Despite their resemblance to small synaptic vesicles of the CNS, a thorough biochemical characterization is lacking. Moreover, the subcellular distribution of synaptophysin, the most abundant integral mem...